NCT05554016 (UFO Project) is a clinical trial in Obesity, Morbid, sponsored by Federico II University.

Who is sponsoring NCT05554016?

NCT05554016 is sponsored by Federico II University.

What condition does NCT05554016 study?

NCT05554016 studies Obesity, Morbid, Metabolic Syndrome.

Is NCT05554016 still recruiting?

NCT05554016 is currently recruiting now. Last updated 4 June 2025.

Last reviewed 2025-06-04 · How we verify

NCT05554016: UFO Project

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The UFO (Ultra Processed Foods in Obesity) Project

Recruiting now Last updated 4 June 2025

What this trial tests

trial in Obesity, Morbid in 200 participants. Currently enrolling.

Timeline

1 September 2022

Primary endpoint
1 September 2025

1 February 2026

Quick facts

Lead sponsor	Federico II University
Status	Recruiting now
Study type	OBSERVATIONAL
Enrollment	200
Start date	1 September 2022
Primary completion	1 September 2025
Estimated completion	1 February 2026
Sites	1 location across Italy

Conditions studied

Obesity, Morbid — all drugs for Obesity, Morbid →
Metabolic Syndrome — all drugs for Metabolic Syndrome →

Sponsor

Federico II University

Who can join

Adults 6 to 18, any sex, with Obesity, Morbid or Metabolic Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The childhood obesity prevalence has increased dramatically in the last decades, affecting more than 340 million children worldwide. This condition is the major risk factor for a set of metabolic abnormalities, also known as metabolic syndrome, a condition that reduce life expectancy by 5-20 years. Changes in the global food system, and the increased consumption of ultra-processed foods (UPFs), may have contributed to the increase in the prevalence of childhood obesity and related morbidities. The mechanisms by which UPFs might promote obesity and metabolic syndrome could be multiple and not completely identified. The Ultra-processed Food in Obesity (UFO) Project has been designed to investigate the potential associations between UPFs intake and MetS in pediatric subjects

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Increased dietary intake of ultraprocessed foods and mitochondrial metabolism alterations in pediatric obesity.
Coppola S, Paparo L, Trinchese G, Rivieri AM, et al · · 2023 · cited 13× · PMID 37537205 · DOI 10.1038/s41598-023-39566-9

Verify or expand the search:

Other recruiting trials for Obesity, Morbid

Currently open trials in the same condition.

NCT07119437 — Low Impact Laparoscopy In Bariatric Surgery · NA · recruiting
NCT05927519 — Comparison of Airtraq in Class 2-3 Obese and Nonobese Men During Intubation: a Prospective Randomized Clinical Study · NA · recruiting
NCT06530212 — Sleeve Gastrectomy With Jejuno-ileal Bypass Versus Single Anastomosis Sleeve Jejunal Bypass · NA · recruiting
NCT06477120 — Time-restricted Eating Among Pregnant Females With Severe Obesity · NA · recruiting
NCT06119516 — Transpulmonary Pressure - Guided Mechanical Ventilation in Morbidly Obese ARDS Patients: a Feasibility Study. · NA · recruiting

Other Federico II University trials

Trials by the same sponsor.

NCT07437690 — Fall Prevention in Older Adults in an Italian Cohort · not yet recruiting
NCT07282132 — Evaluation of Real-World Data on Ropeginterferon Alfa-2b in Patients With Polycythemia Vera: Insights From a Multicenter · not yet recruiting
NCT07280286 — Incidence of Intrauterine Adhesions After Myomectomy With Intrauterine Anti-Adhesion Gel · NA · not yet recruiting
NCT07374861 — Multicenter Study on the Evaluation of Adherence, Persistence and Efficacy of Treatment With Bempedoic Acid in Italy · recruiting
NCT07314684 — GLP1-RAs Effects on Inflammatory and Endothelial Biomarkers in T2DM · Phase 4 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05554016 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Federico II University
Last refreshed: 4 June 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05554016.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing