Who is sponsoring NCT05549492?

NCT05549492 is sponsored by Egymedicalpedia.

What drugs are being tested in NCT05549492?

Interventions in NCT05549492: Ropivacaine 0.25%-NaCl 0.9% Injectable Solution.

What condition does NCT05549492 study?

NCT05549492 studies Inguinal Hernia, Pain, Postoperative.

Is NCT05549492 still recruiting?

NCT05549492 is currently completed. Last updated 22 September 2022.

Last reviewed 2022-09-22 · How we verify

NCT05549492

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Transversus Abdominis Plane Block With or Without Buprenorphine After Inguinal Hernia Surgery

Completed Phase 1 Last updated 22 September 2022

What this trial tests

Phase 1 trial testing Ropivacaine 0.25%-NaCl 0.9% Injectable Solution in Inguinal Hernia in 64 participants. Completed in 30 May 2022.

Timeline

1 January 2021

Primary endpoint
1 May 2022

30 May 2022

Quick facts

Lead sponsor	Egymedicalpedia
Phase	Phase 1
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	64
Start date	1 January 2021
Primary completion	1 May 2022
Estimated completion	30 May 2022
Sites	1 location across Egypt

Drugs / interventions tested

Ropivacaine 0.25%-NaCl 0.9% Injectable Solution — full drug profile →

Conditions studied

Inguinal Hernia — all drugs for Inguinal Hernia →
Pain, Postoperative — all drugs for Pain, Postoperative →

Sponsor

Egymedicalpedia — full company profile →

Who can join

Adults 30 to 45, any sex, with Inguinal Hernia or Pain, Postoperative. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Buprenorphine intravenous, sublingual, and transdermal patches have been researched for their antihyperalgesic effects, although peripherally mediated effects have not been examined in Egypt surprisingly

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Effect of transversus abdominis plane block with or without buprenorphine after inguinal hernia surgery on postoperative pain.
Elshalakany NA, Salah AM. · · 2023 · cited 3× · PMID 38084572 · DOI 10.5114/ait.2023.132837

Verify or expand the search:

Other trials of Ropivacaine 0.25%-NaCl 0.9% Injectable Solution

Trials testing the same drug.

NCT03874806 — Pharmacokinetic Profile and Dermatomal Coverage of the Erector Spinae Plane Block · Phase 4 · withdrawn

Other recruiting trials for Inguinal Hernia

Currently open trials in the same condition.

NCT07473687 — Feasibility Study of Non-Contact Imaging-Based Physiological Monitoring in the Operating Room · recruiting
NCT06915155 — Swing-Mesh™ Study (SMS). · active not recruiting
NCT07346742 — Prevention of Surgical Site Infection in Open Paediatric Groin Surgeries Using Intravenous Prophylactic Antibiotics and · NA · recruiting
NCT06871605 — Transversalis Fascia Plane vs Ilioinguinal and Iliohypogastric Nerve Block for the Treatment of CPIP · NA · recruiting
NCT04706026 — A Pilot Study of Local Anesthesia for Inguinal Hernia Surgery in Older Adults · NA · recruiting

Other Egymedicalpedia trials

Trials by the same sponsor.

NCT06590818 — The Effect of Body Mass Index on Short-term Results of HTO · NA · recruiting
NCT06583811 — Remifentanil and Remimazolam to Limit Patient Movement · NA · recruiting
NCT06522984 — Fractional Erbium YAG Laser vs Intradermal and Systemic Tranexamic Acid · NA · recruiting
NCT06370078 — Effect of Early Administration of Albumin 20% Versus Crystalloid · NA · recruiting
NCT06370221 — The Effect of Psoriatic Arthritis on Female Sexual Dysfunction · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05549492 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Egymedicalpedia
Last refreshed: 22 September 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05549492.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing