Last reviewed · How we verify
NCT05546372: RACCOON
Endobiliary Radiofrequency Ablation for Malignant Biliary Obstruction Due to Perihilar Cholangiocarcinoma
NA trial testing Endobiliary radiofrequency ablation (eRFA) in Perihilar Cholangiocarcinoma in 98 participants. Status unknown.
31 March 2026
Quick facts
| Lead sponsor | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 98 |
| Start date | 9 November 2023 |
| Primary completion | 31 March 2026 |
| Estimated completion | 31 March 2026 |
| Sites | 1 location across Netherlands |
Drugs / interventions tested
- Endobiliary radiofrequency ablation (eRFA)
- uncovered self-expanding metal stent (uSEMS)
Conditions studied
- Perihilar Cholangiocarcinoma — all drugs for Perihilar Cholangiocarcinoma →
Sponsor
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) — full company profile →
Who can join
18 and older, any sex, with Perihilar Cholangiocarcinoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A multicentre, parallel group, open label, randomized controlled trial comparing endobiliary RFA prior to metal stent placement with stent placement only in patients with inoperable perihilar cholangiocarcinoma.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Update on Locoregional Therapies for Cholangiocellular Carcinoma.
Morawitz J, Bruckmann NM, Jannusch K, Kirchner J, et al · · 2023 · cited 5× · PMID 37190295 · DOI 10.3390/cancers15082368
Verify or expand the search:
- PubMed search for NCT05546372
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Perihilar Cholangiocarcinoma
Currently open trials in the same condition.
- NCT06986486 — Liver Transplantation for Unresectable Perihilar Cholangiocarcinoma · recruiting
- NCT06720883 — Robotically Assisted Surgery For Perihilar Cholangiocarcinoma: A Prospective Study · recruiting
- NCT06125769 — LIver TrAnspLantation for Non-resectable Peri-HIlar cholangioCArcinoma (LITALHICA) · NA · recruiting
- NCT05430698 — PD-1 Antibody Plus GEMOX as Postoperative Adjuvant Therapy in Perihilar Cholangiocarcinoma · Phase 2 · recruiting
- NCT04993131 — Liver Transplantation for Non-resectable Perihilar Cholangiocarcinoma · NA · recruiting
Other Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) trials
Trials by the same sponsor.
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- NCT06909045 — Adaptive vs. Continuous Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease · NA · recruiting
- NCT07316127 — Immunoadsorption in Autoimmune Long COVID · Phase 2 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05546372 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
- Last refreshed: 27 October 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05546372.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing