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NCT05544877: B2B
An Energetic View on Creativity, Psychopathology and Intelligence: The Brain2Business Study
NA trial testing Integrated 5-day Gratitude Exercise and Behavioral Activation Program in General Psychopathology in 200 participants. Completed in 4 October 2023.
29 September 2023
Quick facts
| Lead sponsor | Psychiatrische Dienste Thurgau |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | supportive care |
| Enrollment | 200 |
| Start date | 19 July 2022 |
| Primary completion | 29 September 2023 |
| Estimated completion | 4 October 2023 |
| Sites | 1 location across Switzerland |
Drugs / interventions tested
- Integrated 5-day Gratitude Exercise and Behavioral Activation Program
Conditions studied
- General Psychopathology — all drugs for General Psychopathology →
- Fatigue — all drugs for Fatigue →
- Depressive Disorder, Major — all drugs for Depressive Disorder, Major →
Sponsor
Psychiatrische Dienste Thurgau
Who can join
18 and older, any sex, with General Psychopathology or Fatigue. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The interventional part of the study aims to assess the acute effect of the Brain2Business (B2B) tool on creative thinking (primary objective) in adults with psychological disorders. Additionally, the study assesses the B2B effects on energy-related sensations and metabolism, technique adherence, gratefulness and goal-directed activation (secondary objectives) in adults with and without psychological disorders. The observational part of the study primarily aims to investigate the link between psychopathology, intelligence, energy-related sensations and metabolism validating the "c factor mito-bioenergetics" (CMB) model in a sample of adults with and without psychological disorders.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
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The effort of maintaining the defensive wall: is there a link between defense mechanisms and vitality?
Vandersmissen A, Fissler Plischke P, Filippi M, Wenzel M, et al · · 2026 · PMID 42106684 · DOI 10.1186/s12888-026-08146-2
Verify or expand the search:
- PubMed search for NCT05544877
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05544877 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Psychiatrische Dienste Thurgau
- Last refreshed: 26 October 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05544877.
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