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NCT05541991
Study on the Effect of Rhubarb Extract on Stool Frequency and Biological Markers of Intestinal Function in Seniors With Low Defecation
NA trial testing single dose coated tablet Fruits & Fibres Rhubarbe with standardised rhubarb extract in Constipation - Functional in 45 participants. Completed in 13 June 2018.
14 March 2018
Quick facts
| Lead sponsor | ortis |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 45 |
| Start date | 10 February 2017 |
| Primary completion | 14 March 2018 |
| Estimated completion | 13 June 2018 |
| Sites | 1 location across France |
Drugs / interventions tested
- single dose coated tablet Fruits & Fibres Rhubarbe with standardised rhubarb extract
- placebo coated tablet
- double dose coated tablet Fruits & Fibres Rhubarbe with standardised rhubarb extract
Conditions studied
- Constipation - Functional — all drugs for Constipation - Functional →
Sponsor
ortis — full company profile →
Who can join
Adults 50 to 70, any sex, with Constipation - Functional. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Randomized double-blind clinical study versus placebo evaluating the effect of supplementation with rhubarb extract on stool frequency and biological markers of intestinal function in seniors with a low number of defecations per week
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Constipation Mitigation by Rhubarb Extract in Middle-Aged Adults Is Linked to Gut Microbiome Modulation: A Double-Blind Randomized Placebo-Controlled Trial.
Neyrinck AM, Rodriguez J, Taminiau B, Herpin F, et al · · 2022 · cited 10× · PMID 36499011 · DOI 10.3390/ijms232314685
Verify or expand the search:
- PubMed search for NCT05541991
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Constipation - Functional
Currently open trials in the same condition.
- NCT07300423 — Parents of Children With Constipation Will be Asked About Their Views on Their Children's Physical Activity. · recruiting
- NCT07126327 — Peristeen Light Explorative Clinical Investigation · NA · recruiting
- NCT07387952 — The Safety and Efficacy of Fecal Microbiota Transplantation Combined With Nutritional Intervention in the Treatment of F · NA · recruiting
- NCT07340203 — Cross-Cultural Adaptation, Validity, and Reliability of the Wexner Questionnaire in Patients With Constipation · active not recruiting
- NCT07077044 — The Effects of TTNS, TTNS Combined With PHUS, and Conventional Therapy With PHUS in the Treatment of PFC. · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05541991 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by ortis
- Last refreshed: 15 September 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05541991.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing