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NCT05540977
Donepezil Prevents Urinary Retention After Extensive Total Hysterectomy
EARLY_PHASE1 trial testing Donepezil in Urinary Retention After Procedure in 108 participants. Status unknown.
31 May 2023
Quick facts
| Lead sponsor | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
|---|---|
| Phase | EARLY_PHASE1 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 108 |
| Start date | 1 August 2022 |
| Primary completion | 31 May 2023 |
| Estimated completion | 15 July 2023 |
| Sites | 1 location across China |
Drugs / interventions tested
- Donepezil (DONEPEZIL) — full drug profile →
- Usual care
Conditions studied
- Urinary Retention After Procedure — all drugs for Urinary Retention After Procedure →
Sponsor
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Who can join
Adults 18 to 80, female only, with Urinary Retention After Procedure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Patients were randomly divided into experimental group and control group. The control group received routine postoperative treatment, while the experimental group took donepezil 5mg orally before going to bed every night from the first day after surgery. The catheter was removed and residual urine was measured in both groups 14 days after surgery, the catheter was successfully removed when the residual urine was less than 100ml. After 14 days, the patient was returned to the hospital for residual urine test, and the residual urine was repeated until the residual urine volume was less than or equal to 100ml. The incidence of postoperative urinary retention and adverse drug reactions were compared between the two groups.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05540977
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Other recruiting trials for Urinary Retention After Procedure
Currently open trials in the same condition.
- NCT06948409 — NMBA Reversal and Postoperative Urinary Retention · active not recruiting
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05540977 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
- Last refreshed: 15 September 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05540977.
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