NCT05539508: PERISCE

Role of Peripheral Vision in Scene Perception (PERISCE)

Not yet recruiting Last updated 14 September 2022

What this trial tests

trial testing Psychophysical evaluation in Primary Open-angle Glaucoma (POAG) in 120 participants. Not yet recruiting.

Timeline

1 October 2022

Primary endpoint
1 July 2026

1 July 2027

Quick facts

Lead sponsor	University Hospital, Grenoble
Status	Not yet recruiting
Study type	OBSERVATIONAL
Enrollment	120
Start date	1 October 2022
Primary completion	1 July 2026
Estimated completion	1 July 2027

Drugs / interventions tested

• Psychophysical evaluation

Conditions studied

• Primary Open-angle Glaucoma (POAG) — all drugs for Primary Open-angle Glaucoma (POAG) →

Sponsor

University Hospital, Grenoble

Who can join

Adults 18 to 80, any sex, with Primary Open-angle Glaucoma (POAG). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Despite its low spatial resolution, peripheral vision is very useful for rapidly categorizing a visual scene. Low spatial frequencies of a visual stimulus available in peripheral vision would allow a coarse categorization of the scene and objects (deciding, for example, whether it is an urban or natural landscape). This first representation would then trigger predictive mechanisms which would subsequently guide a more detailed visual analysis in central vision. The psychophysical studies that the investigators have already conducted in this scientific context has been carried out under normal vision conditions. The objective of this project is to study the influence of peripheral vision on central vision with an original approach: What are the consequences of a loss of peripheral vision on the processing performed in central vision? The project will concern patients with glaucoma. This ophthalmic pathology particularly affects the peripheral retina and thus represents a good pathological cognitive model of a visual recognition system in which peripheral vision is less important. The investigators will conduct psychophysical studies with glaucomatous patients and healthy volunteers with normal vision. All participants will be required to perform a short experiment on a computer (15 minutes) where they will look at different photographs of scenes of different luminance and spatial frequencies. Participants will have to perform various tasks on these images using the keys on the keyboard.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.