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NCT05538858
Vascular Injury in Mechanical Ventilation: a Proof-of-Concept Study
trial testing Mechanical Ventilation in Mechanical Ventilation Complication in 19 participants. Completed in 19 May 2023.
19 May 2023
Quick facts
| Lead sponsor | University of Manitoba |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 19 |
| Start date | 15 December 2022 |
| Primary completion | 19 May 2023 |
| Estimated completion | 19 May 2023 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Mechanical Ventilation
Conditions studied
- Mechanical Ventilation Complication — all drugs for Mechanical Ventilation Complication →
- Vascular Injury — all drugs for Vascular Injury →
- Endothelial Dysfunction — all drugs for Endothelial Dysfunction →
Sponsor
University of Manitoba
Who can join
18 and older, any sex, with Mechanical Ventilation Complication or Vascular Injury. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Investigation of the effect of mechanical ventilation on biomarkers of microvascular damage
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05538858
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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- Google Scholar
Related trials
Other trials of Mechanical Ventilation
Trials testing the same drug.
- NCT05321888 — Mechanical Ventilation With and Without Postural Drainage in Burn Patients With ARDS · NA · completed
- NCT04241874 — PEEP and Spontaneous Breathing During ARDS · NA · completed
- NCT04026451 — Spectral Edge Frequency From Spectral EEG Analysis to Guide Deep Sedation in the Critical Care Setting (Pilot) · NA · withdrawn
- NCT03401736 — The Diversity of Intestinal Microbiota in Patients With Different Sedative-hypnotics Undergoing Mechanical Ventilation · NA · withdrawn
- NCT02989415 — Assessment of Ventilatory Management During General Anesthesia for Robotic Surgery · completed
Other recruiting trials for Mechanical Ventilation Complication
Currently open trials in the same condition.
- NCT06921655 — Targeting prEssure-Muscle-index to Avoid Ventilatory Over-Assistance During Pressure Support Ventilation · NA · recruiting
- NCT07207772 — EIT-guided PEEP Titration Versus Standard Ventilation in Bariatric Surgery · NA · recruiting
- NCT07182851 — Prevalence of Pain in Mechanically Ventilated Patients in Intensive Care Units · recruiting
- NCT06575530 — Sedation Efficacy and Safety of Remazolam Besylate in Ventilated Surgical Critically Ill Patients · Phase 4 · recruiting
- NCT06592144 — TESTO-TRIAL: Use of Testosterone in Critically Ill Patients · Phase 4 · active not recruiting
Other University of Manitoba trials
Trials by the same sponsor.
- NCT07528417 — Evaluation of Antibiotic Prophylaxis in Myelodysplastic Syndromes and Acute Myeloid Leukemia (MYELO-CAN:ABX) · Phase 2 · not yet recruiting
- NCT07366515 — Feasibility of a Multimodal Virtual Reality Intervention to Reduce Preoperative Anxiety in Cancer Surgery Patients · NA · not yet recruiting
- NCT07354386 — Effects of Dried Whole Fruits on Metabolism in Diabetes · NA · enrolling by invitation
- NCT07361315 — Development and Online Evaluation of an Online Course for Parasomnias · NA · recruiting
- NCT07023744 — CANnabinoids for Drug Resistant Epilepsy (DRE) in Adults and Children · Phase 2 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05538858 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Manitoba
- Last refreshed: 24 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05538858.
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