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NCT05537909: ABSCESSBIOT
Role of Gut Microbiota in the Pathophysiology of Aseptic Abscesses
NA trial testing Biological sample collection in Aseptic Abscess Syndrome in 60 participants. Status unknown.
31 December 2024
Quick facts
| Lead sponsor | University Hospital, Clermont-Ferrand |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 60 |
| Start date | 7 September 2021 |
| Primary completion | 31 December 2024 |
| Estimated completion | 31 December 2025 |
| Sites | 15 locations across France |
Drugs / interventions tested
- Biological sample collection — full drug profile →
Conditions studied
- Aseptic Abscess Syndrome — all drugs for Aseptic Abscess Syndrome →
Sponsor
University Hospital, Clermont-Ferrand
Who can join
18 and older, any sex, with Aseptic Abscess Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Aseptic abscess syndrome (AA) is a rare entity characterized by the occurrence of deep abscesses with no germ found. Antibiotic therapy is ineffective and they are sensitive to anti-inflammatory treatment with corticosteroids. Gut microbiota is important for the development of the immune system. In Crohn's disease which is frequently associated with AA syndrome, dysbiosis is found but could also be involved in the immune response at a distance from the gut. Stool, blood, saliva and urine samples will be taken from the patients included and their controls in the centers where they are followed. These biological samples will be transported to Clermont Ferrand using the same procedure (transporter and dry ice) where the following analyses will be performed: microbiota on stool and saliva, short chain fatty acids on stool and lymphocyte study on blood.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Host-microbiota relationship in the pathophysiology of aseptic abscess syndrome: protocol for a multicentre case-control study (ABSCESSBIOT).
Trefond L, Billard E, Pereira B, Richard D, et al · · 2023 · cited 3× · PMID 37541750 · DOI 10.1136/bmjopen-2023-073776
Verify or expand the search:
- PubMed search for NCT05537909
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05537909 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Clermont-Ferrand
- Last refreshed: 19 September 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05537909.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing