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NCT05533723
Comparison Between Endoscopic Epidural Neuroplasty and Percutaneous Epidural Neuroplasty in Low Back and Radicular Pain
trial testing Endoscopic epidural neuroplasty in Low Back Pain in 107 participants. Completed in 24 August 2022.
24 August 2022
Quick facts
| Lead sponsor | Ajou University School of Medicine |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 107 |
| Start date | 10 October 2018 |
| Primary completion | 24 August 2022 |
| Estimated completion | 24 August 2022 |
| Sites | 1 location across South Korea |
Drugs / interventions tested
- Endoscopic epidural neuroplasty
- Percutaneous epidural neuroplasty (PEN)
Conditions studied
- Low Back Pain — all drugs for Low Back Pain →
- Radiculopathy — all drugs for Radiculopathy →
Sponsor
Ajou University School of Medicine
Who can join
Eligibility, any sex, with Low Back Pain or Radiculopathy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
PEN(percutaneous epidural neuroplasty) can be performed percutaneously, may be manipulated to mechanically break up adhesions by catheter, while various agents, such as anesthetics, corticosteroids, hyaluronidase, and hypertonic saline are injected. In endoscopic epidural neuroplasty (EEN), a flexible catheter is inserted into the sacral hiatus to precisely place the injection in the epidural space and onto the nerve root. Both EEN and PEN can eliminate the deleterious effects of scar formation, which can physically prevent the direct application of drugs to the nerves, and may provide pain relief in patients who have not responded to epidural blocks, physical therapy, or medication. In this study, visual analog scale (VAS) and Oswestry disability index (ODI) of patients with low back and radicular pain were compared in patients who had received EEN or PEN at 1 day, 1 month, and 6 months after EEN or PEN.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A Comparative Study of Endoscopic versus Percutaneous Epidural Neuroplasty in Lower Back Pain: Outcomes at Six-Month Follow Up.
Choi JB, Koh JC, Jo D, Kim JH, et al · · 2024 · cited 3× · PMID 38793022 · DOI 10.3390/medicina60050839
Verify or expand the search:
- PubMed search for NCT05533723
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Ajou University School of Medicine trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05533723 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ajou University School of Medicine
- Last refreshed: 9 September 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05533723.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing