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NCT05529511: POP-ACLR

The PreOperative Management of Patients Awaiting Anterior Cruciate Ligament Reconstruction

Completed Results posted Last updated 15 April 2025
What this trial tests

trial testing Phase 1 - semi-structured interviews in Anterior Cruciate Ligament Injuries in 26 participants. Completed in 4 September 2023.

Timeline
3 August 2022
Primary endpoint
30 August 2023
4 September 2023

Quick facts

Lead sponsorUniversity Hospitals of Derby and Burton NHS Foundation Trust
StatusCompleted
Study typeOBSERVATIONAL
Enrollment26
Start date3 August 2022
Primary completion30 August 2023
Estimated completion4 September 2023
Sites1 location across United Kingdom

Drugs / interventions tested

Conditions studied

Sponsor

University Hospitals of Derby and Burton NHS Foundation Trust

Who can join

18 and older, any sex, with Anterior Cruciate Ligament Injuries or Anterior Cruciate Ligament Rupture. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Number of Participants Who Completed Semi-structured Interviews Primary · Interviews completed within approximately 60 minutes

Understanding of patients' lived experiences of the treatment pathway following a diagnosis of an ACL rupture and agreed surgical management. Qualitative data collected from individual semi-structured interviews.

Explore patient experiences of preoperative treatment
GroupValue95% CI
Phase 1 - Preoperative18
Phase 2 - Nominal Group Technique Panel0
Explore patient experiences of postoperative treatment
GroupValue95% CI
Phase 1 - Preoperative8
Explore views and involvement in prehabilitation
GroupValue95% CI
Phase 1 - Preoperative12
Explore sources and consistency of healthcare advice
GroupValue95% CI
Phase 1 - Preoperative18
Number of Participants in the Nominal Group Technique Panel Primary · Two online meetings completed, up to 2 hours on 2 days approximately 1-month apart.

Intervention developed with clinicians, patients and stakeholders for use with patients awaiting anterior cruciate ligament reconstruction in the National Health Service (NHS). Consensus was determined through voting set at an 70% threshold.

Patient participants
GroupValue95% CI
Phase 1 - Preoperative0
Phase 2 - Nominal Group Technique Panel2
Clinician participants
GroupValue95% CI
Phase 1 - Preoperative0
Phase 2 - Nominal Group Technique Panel5
Therapy manager participant
GroupValue95% CI
Phase 1 - Preoperative0
Phase 2 - Nominal Group Technique Panel1

Sponsor's own description

Patient experiences of the NHS ACL treatment pathway are unknown. This study aims to explore patient experiences of anterior cruciate ligament ruptures at three different time points on the patient pathway: (1) 12 participants up to 2 weeks before surgery, (2) 12 participants 3 months after surgery, (3) 12 participants 12 months after surgery.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. 'Going through the motions'; a rich account of the complexity of the anterior cruciate ligament reconstruction pathway, a UK qualitative study.
    Carter HM, Beard DJ, Leighton P, Moffatt F, et al · · 2024 · cited 3× · PMID 39289010 · DOI 10.1136/bmjopen-2023-079468
  2. Development of an intervention for patients following an anterior cruciate ligament rupture: an online nominal group technique consensus study.
    Carter H, Beard D, Leighton P, Moffatt F, et al · · 2024 · cited 1× · PMID 39025812 · DOI 10.1136/bmjopen-2023-082387

Verify or expand the search:

Other recruiting trials for Anterior Cruciate Ligament Injuries

Currently open trials in the same condition.

Other University Hospitals of Derby and Burton NHS Foundation Trust trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05529511.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing