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NCT05528159
Lung Ultrasound Score (LUS) Change in Robotic and Laparoscopic Urologic Surgeries
trial testing Intraabdominal CO2 insufllation in Atelectasis in 48 participants. Completed in 30 April 2024.
15 April 2024
Quick facts
| Lead sponsor | Istanbul University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 48 |
| Start date | 7 December 2022 |
| Primary completion | 15 April 2024 |
| Estimated completion | 30 April 2024 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Intraabdominal CO2 insufllation
Conditions studied
- Atelectasis — all drugs for Atelectasis →
Sponsor
Istanbul University
Who can join
18 and older, any sex, with Atelectasis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Robotic and laparoscopic surgeries are tend to cause lung atelectasis due to the insufflation of CO2 into abdomen. However, ultrasonographic measurement for this phenomenon and its clinical use is not well investigated. In this particular study, It is aimed to observe lung ultrasound score (LUS) changes in robotic and laparoscopic supine position surgeries such as prostatectomies and cystectomies. LUS is a pragmatic measurement method that calculates the degree of atelectasis and consolidation in the lungs. Both hemithoraxes are separated into 3 different segments with vertical lines (one between the parasternal line and anterior axillary line, one between the anterior and posterior axillary line, and one posterior to the posterior axillary line). These vertical segments are also divided into two with an horizontal line on the nipple. Lung ultrasonography is applied in all 12 zones for both lungs in the intercostal regions and a scoring system is used. Accordingly, pure A lines (transverse frequent lines) reflects normal lung tissue with no consolidation and scored as zero points (Also named "A"). If less than 4 B lines (vertical lines reflecting some degree of consolidation) is observed, it refers to 1 point (named "B1"). 4 or more B lines refers to 2 points (B2), and if wide and coalesced B lines or patchy pleural line is observed that refers to 3 points (C). All evaluations will be made in supine position. In this trial, LUS will be applied in three different time points: T1: 5 minutes after orotracheal intubation T2: At the end of surgery, before extubation (under deep anesthetic state) T3: 30 minutes after extubation, in postanesthesia care unit During the surgery and the postoperative care period standart monitorization and mechanical ventilation data will be gathered. Also intraoperative and postoperative blood gas analysis will be obtained to observe oxygenation changes. This study is planned as a prospective observational study and our hypothesis is that LUS scores would be lower in acute postoperative period with robotic and laparoscopic surgeries. Therefore primary outcome is the numeric change in T3 and T1. Secondarily, LUS scores will be evaluated between robotic group and laparoscopic group patients for all time points.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Evaluation of perioperative lung ultrasound scores in robotic radical prostatectomy: prospective observational study.
Vuran Yaz İ, Bingül ES, Canbaz M, Aygün E, et al · · 2025 · PMID 40069409 · DOI 10.1007/s11701-025-02272-x
Verify or expand the search:
- PubMed search for NCT05528159
- Europe PMC full search
- ASCO Meeting Library
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05528159 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Istanbul University
- Last refreshed: 9 July 2024
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