Last reviewed · How we verify
NCT05523375: PROPEL-IT
Promoting Successful Weight Loss in Primary Care in Louisiana Using Information Technology
NA trial testing Intensive Lifestyle Intervention in Obesity in 352 participants. Participants enrolled and being followed up; not accepting new ones.
31 March 2026
Quick facts
| Lead sponsor | Pennington Biomedical Research Center |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 352 |
| Start date | 29 August 2022 |
| Primary completion | 31 March 2026 |
| Estimated completion | 31 March 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Intensive Lifestyle Intervention
Conditions studied
- Obesity — all drugs for Obesity →
- Diabetes Mellitus, Type 2 — all drugs for Diabetes Mellitus, Type 2 →
- PreDiabetes — all drugs for PreDiabetes →
Sponsor
Pennington Biomedical Research Center — full company profile →
Who can join
Adults 40 to 70, any sex, with Obesity or Diabetes Mellitus, Type 2. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The primary aim is to test the effectiveness of an innovative 24-month pragmatic and scalable weight-loss centric approach using a collaborative care model that connects patients with a non-Primary Care Practitioner (PCP) health coach who delivers care remotely to patients through the patient portal of an electronic medical record (EMR).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Improving weight loss and cardiometabolic risk in black patients with diabetes or pre-diabetes: Rationale and protocol for a digital medicine hybrid type 1 implementation trial.
Katzmarzyk PT, Price-Haywood EG, Apolzan JW, Denstel KD, et al · · 2025 · PMID 39756673 · DOI 10.1016/j.cct.2024.107806
Verify or expand the search:
- PubMed search for NCT05523375
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Intensive Lifestyle Intervention
Trials testing the same drug.
- NCT06921304 — BASE-DIET: a Study on Nutritional Intervention in Patients With Graves' Disease · NA · active not recruiting
- NCT04116905 — Intensive Lifestyle Intervention for Remission of Metabolic Syndrome · NA · completed
- NCT04457440 — Cognitive Behavioral Sleep Intervention for Prevention of Type 2 Diabetes · NA · suspended
- NCT02615353 — Preventing Diabetes in Latino Youth · NA · completed
- NCT02409238 — Insulin Resistance and Mild Cognitive Impairment (IRMCI) Study · Phase 4 · terminated
Other recruiting trials for Obesity
Currently open trials in the same condition.
- NCT07403604 — Effect of Insulin Lowering on Lipogenesis · Phase 1 · recruiting
- NCT07509307 — AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee · Phase 3 · recruiting
- NCT07272837 — Impact of Semaglutide (Ozempic/Wegovy®) on Heart and Muscle Mass · recruiting
- NCT07481630 — A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoart · Phase 3 · recruiting
- NCT07527195 — Understanding the Effect of CagriSema, Cagrilintide, and Semaglutide on Muscle Health (Role of Amylin Signature in Muscl · Phase 1 · recruiting
Other Pennington Biomedical Research Center trials
Trials by the same sponsor.
- NCT07530718 — Body Composition Outcomes in MS Patients · not yet recruiting
- NCT07095972 — Continuous Glucose Monitoring in Metabolic Surgery · NA · not yet recruiting
- NCT07139821 — Dietary Iron Requirements · recruiting
- NCT07318064 — Ultra-processed Food Consumption and Health Pilot Study · NA · not yet recruiting
- NCT07305753 — CanCan Body Composition Study · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05523375 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Pennington Biomedical Research Center
- Last refreshed: 17 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05523375.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing