NCT05517694: premature

Effect of Respiratory Exercises On The Intravaginal Ejaculation Latency Time

Completed NA Last updated 2 February 2023

What this trial tests

NA trial testing Pelvic floor exercises and behavioral therapy in Premature Ejaculation in 59 participants. Completed in 15 January 2023.

Timeline

10 January 2022

Primary endpoint
5 January 2023

15 January 2023

Quick facts

Lead sponsor	Bahçeşehir University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	59
Start date	10 January 2022
Primary completion	5 January 2023
Estimated completion	15 January 2023
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

• Pelvic floor exercises and behavioral therapy
• Respiratory exercises

Conditions studied

• Premature Ejaculation — all drugs for Premature Ejaculation →

Sponsor

Bahçeşehir University

Who can join

Adults 20 to 45, male only, with Premature Ejaculation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

According to recent epidemiological studies, premature ejaculation (PE) is accepted as the most common sexual dysfunction in men, with a frequency of up to 20%.According to the definition made by the International Society for Sexual Medicine (ISSM) in 2014, PE: 'Ejaculation (lifelong PE) that is always or almost always around 1 minute after the first sexual experience, or, ejaculation time can be reduced to 3 minutes.

Male pelvic floor muscle function also plays a role in coordinating ejaculation. Pelvic floor therapy has been found to improve control over ejaculation and increase intravaginal ejaculatory delay times (IELT) in men with premature ejaculation and pelvic floor muscle dysfunction.

Behavioral treatments consist of physical techniques that will help men's sexual development, delaying ejaculation and increasing sexual self-confidence. Specific physical techniques include: The "stop-start" technique developed by Semans involves the person or their partner, the penis is stimulated until you feel the urge to ejaculate, then it stops until the feeling goes away and the feeling goes away; this is repeated several times before allowing ejaculation to occur.

The pelvic floor muscles have respiratory functions, and most of them have been investigated in studies on urological diseases. Focusing on lower abdominal respiration, it was observed that it was associated with a significant increase in whole blood serotonin 5-hydroxytryptamine (5-HT) levels . One hypothesis proposed for the pathophysiology of premature ejaculation is that high 5-HT is associated with ejaculatory control.

Our purpose is to investigate the effect of adding breathing exercises in addition to pelvic floor rehabilitation and behavioral treatment methods on ejaculation time in individuals with premature ejaculation.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.