NCT05517187 (PRF) is a NA clinical trial of no intervention in Dental Pulp Necroses, sponsored by Nahda University.

Who is sponsoring NCT05517187?

NCT05517187 is sponsored by Nahda University.

What drugs are being tested in NCT05517187?

Interventions in NCT05517187: no intervention, Platelet rich fibrin.

What condition does NCT05517187 study?

NCT05517187 studies Dental Pulp Necroses.

Is NCT05517187 still recruiting?

NCT05517187 is currently status unknown. Last updated 31 August 2022.

Last reviewed 2022-08-31 · How we verify

NCT05517187: PRF

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Efficacy of Regenerative Endodontic Treatment With PRF as a Secondary Treatment of Mature Necrotic Incisors in Adolescents

Status unknown NA Last updated 31 August 2022

What this trial tests

NA trial testing no intervention in Dental Pulp Necroses in 40 participants. Status unknown.

Timeline

10 March 2022

Primary endpoint
1 March 2023

1 March 2023

Quick facts

Lead sponsor	Nahda University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	40
Start date	10 March 2022
Primary completion	1 March 2023
Estimated completion	1 March 2023
Sites	2 locations across Egypt

Drugs / interventions tested

no intervention
Platelet rich fibrin — full drug profile →

Conditions studied

Dental Pulp Necroses — all drugs for Dental Pulp Necroses →

Sponsor

Nahda University

Who can join

Adults 11 to 18, any sex, with Dental Pulp Necroses. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Evalaution of clinical success of secondary treatment for total 40 permanent incisors with failed root canal treatment with apical radiolucency. Twenty of of these permanent incisors will be treated with regenerative endodontic treatment(RET) with platelets rich fibrin PRF as intervention group vs. 20 incisors control group secondary treated with (RET) with induced blood clot (BC).

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Change in the size of apical radiolucencies in adolescent's mature maxillary incisors following retreatment with two regenerative endodontic techniques: a 12-month randomised clinical trial using volume-based cone-beam computed tomography.
Wahba NKO, Bahnasy SSEL, ElMakawi YM, Dummer PMH, et al · · 2025 · cited 2× · PMID 40319119 · DOI 10.1007/s00784-025-06344-y
Postoperative pain after pulpotomy versus pulpectomy of primary molars with symptomatic irreversible pulpitis: an equivalent randomized clinical trial.
Sermani DI, Abdelmotelb MA, Elheeny AAH. · · 2026 · PMID 42035058 · DOI 10.1186/s12903-026-08329-z

Verify or expand the search:

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Other Nahda University trials

Trials by the same sponsor.

NCT07086235 — Remineralization Capacity and Patient Satisfaction of Self-Assembling Peptide With Fluoride Versus Tooth Protective Coat · NA · completed
NCT05623605 — Evaluation of New Different Herbal Mouthwashes Against Caries Forming Bacteria, RCT · Phase 4 · unknown
NCT05657132 — Antibacterial Effect of New Herbal Paste Used as an Intracanal Medication · Phase 3 · unknown
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NCT04073901 — Comparative Study Between Zirconia Crowns and Endocrowns in Pulpotomized Primary Molars · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05517187 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Nahda University
Last refreshed: 31 August 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05517187.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing