Pilot Trial of Intra-articular Stromal Vascular Fraction for the Treatment of Knee Post-Trauma Osteoarthritis and Biomarker Identification (SVF)

NCT05515523 EARLY_PHASE1 WITHDRAWN

This is a prospective, non-randomized, interventional, dual site, before-after clinical trial to determine feasibility and safety of a single injection of autologous Adipose Derived (AD) Stromal Vascular Fraction (SVF) for the treatment of knee Post Traumatic Osteoarthritis (PTOA).

Details

Lead sponsor	Wake Forest University Health Sciences
Phase	EARLY_PHASE1
Status	WITHDRAWN
Start date	2026-02
Completion	2027-11

Conditions

• Osteoarthritis

Interventions

• Adipose Derived (AD) Stromal Vascular Fraction (SVF)

Primary outcomes

• Number of Adverse Events — Year 1
  number of safety events post injection

Countries

United States