Who is sponsoring NCT05514197?

NCT05514197 is sponsored by Chimei Medical Center.

What drugs are being tested in NCT05514197?

Interventions in NCT05514197: Ascorbic acid 100mg/kg, Maximus 10g, Control Rx.

What condition does NCT05514197 study?

NCT05514197 studies Ascorbic Acid, Postoperative Pain.

Is NCT05514197 still recruiting?

NCT05514197 is currently completed. Last updated 19 November 2025.

Last reviewed 2025-11-19 · How we verify

NCT05514197

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Impact of Intravenous Vitamin C Combined With Nerve Blocks on Postoperative Pain and Recovery After Total Knee Arthroplasty

Completed NA Last updated 19 November 2025

What this trial tests

NA trial testing Ascorbic acid 100mg/kg, Maximus 10g in Ascorbic Acid in 73 participants. Completed in 11 January 2024.

Timeline

2 November 2022

Primary endpoint
13 December 2023

11 January 2024

Quick facts

Lead sponsor	Chimei Medical Center
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	73
Start date	2 November 2022
Primary completion	13 December 2023
Estimated completion	11 January 2024
Sites	1 location across Taiwan

Drugs / interventions tested

Ascorbic acid 100mg/kg, Maximus 10g — full drug profile →
Control Rx — full drug profile →

Conditions studied

Ascorbic Acid — all drugs for Ascorbic Acid →
Postoperative Pain — all drugs for Postoperative Pain →

Sponsor

Chimei Medical Center

Who can join

Adults 50 to 80, any sex, with Ascorbic Acid or Postoperative Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this prospective randomized-control study was to evaluate the impact of a single high-dose intravenous vitamin C added to ultrasound-guided blocks at induction on postoperative pain, sngception and early functional rehabilitation of the knee joint in patients under-going total knee arthroplasty.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other Chimei Medical Center trials

Trials by the same sponsor.

NCT06666361 — Middle-aged and Older Adults with Hypertension in Rural Communities · NA · recruiting
NCT06447441 — Clinical Outcomes Of Mega-dosage Supplementations Of Cholecalciferol In Critically Ill Patients With Sepsis · NA · not yet recruiting
NCT05493774 — Preliminary Exploration of Applying Multi-person Simulation Training to Improve Nurse-led Burn and Scald Nursing Care · NA · completed
NCT06907004 — Developing a Exercise Program for Patients Undergoing Hematopoietic Stem Cell Transplantation · completed
NCT06429020 — Sonography for COVID-19 Vaccines Related Reactive Lymphadenopathy · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05514197 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Chimei Medical Center
Last refreshed: 19 November 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05514197.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing