Last reviewed · How we verify

NCT05511402

Effect of Aerobic Training on Oxidative Stress Markers in Patients With Parkinson's Disease

Status unknown NA Last updated 25 August 2022
What this trial tests

NA trial testing Exercise training in Parkinson Disease in 28 participants. Status unknown.

Timeline
25 August 2022
Primary endpoint
30 November 2022
10 December 2022

Quick facts

Lead sponsorSaglik Bilimleri Universitesi
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingsingle
Primary purposetreatment
Enrollment28
Start date25 August 2022
Primary completion30 November 2022
Estimated completion10 December 2022
Sites1 location across Turkey (Türkiye)

Drugs / interventions tested

Conditions studied

Sponsor

Saglik Bilimleri Universitesi — full company profile →

Who can join

40 and older, any sex, with Parkinson Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Parkinson's disease is a chronic, neurodegenerative disorder characterized with the loss of dopamine-producing neurons. This loss is likely to be related with several environmental and genetic factors. One of the most important factor that is responsible for the initation and progression of the disease is oxidative stress. Exercise training, especially aerobic training, can change the levels of oxidative markers because exercise can lead to decrease oxidative stress in patients with Parkinson's disease. Therefore, this study aims to investigate (1) the effect of aerobic training on total antioxidant status, total oxidant status, glutathione, oxidative glutathione, and zonulin levels, (2) the relationship between the change of motor symptoms and disease severity and the change of total antioxidant status, total oxidant status, glutathione, oxidative glutathione, and zonulin levels.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Clinical Trial Highlights - Aerobic Exercise for Parkinson's Disease.
    Schootemeijer S, Darweesh SKL, de Vries NM. · · 2022 · cited 6× · PMID 36336942 · DOI 10.3233/jpd-229006

Verify or expand the search:

Other trials of Exercise training

Trials testing the same drug.

Other recruiting trials for Parkinson Disease

Currently open trials in the same condition.

Other Saglik Bilimleri Universitesi trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05511402.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing