NCT05511272 (CIRCAPRO) is a NA clinical trial of blood test in Fertility Disorders, sponsored by Universitair Ziekenhuis Brussel.

Who is sponsoring NCT05511272?

NCT05511272 is sponsored by Universitair Ziekenhuis Brussel.

What drugs are being tested in NCT05511272?

Interventions in NCT05511272: blood test.

What condition does NCT05511272 study?

NCT05511272 studies Fertility Disorders.

Is NCT05511272 still recruiting?

NCT05511272 is currently completed. Last updated 19 December 2023.

Last reviewed 2023-12-19 · How we verify

NCT05511272: CIRCAPRO

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Circadian Variability of Serum Progesterone During the Day of a Frozen Embryo Transfer

Completed NA Last updated 19 December 2023

What this trial tests

NA trial testing blood test in Fertility Disorders in 44 participants. Completed in 1 December 2023.

Timeline

15 August 2022

Primary endpoint
1 December 2023

1 December 2023

Quick facts

Lead sponsor	Universitair Ziekenhuis Brussel
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	44
Start date	15 August 2022
Primary completion	1 December 2023
Estimated completion	1 December 2023
Sites	1 location across Belgium

Drugs / interventions tested

blood test — full drug profile →

Conditions studied

Fertility Disorders — all drugs for Fertility Disorders →

Sponsor

Universitair Ziekenhuis Brussel — full company profile →

Who can join

Adults 18 to 40, female only, with Fertility Disorders. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Serum progesterone levels will be evaluated at four different time points during the day of an artificially prepared frozen embryo transfer cycle (HRT FET cycle) and a modified natural cycle frozen embryo transfer cycle (mNC FET cycle) (at 08:00, 12:00, 16:00 and 20:00).The pairwise percentage differences in serum progesterone levels for each patient will be calculated. The intra-day variability of progesterone will be analyzed using mixed models. Pregnancy outcomes will also be assessed. The sample size calculated consisted of 22 patients for the HRT-FET study and 22 patients for the mNC FET study.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Circadian serum progesterone variations on the day of frozen embryo transfer in a modified natural cycle protocol.
Loreti S, Roelens C, Aktoz F, Niero M, et al · · 2024 · cited 2× · PMID 38775072 · DOI 10.1093/humrep/deae101

Verify or expand the search:

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Currently open trials in the same condition.

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Other Universitair Ziekenhuis Brussel trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05511272 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Universitair Ziekenhuis Brussel
Last refreshed: 19 December 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05511272.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing