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Effectiveness of Different Postoperative Analgesics Use in the Management of Acute Pain After Ureteroscopy.
In this study, we will see the feasibility of a non-opioid pain killers in management of acute post-operative period as well as on discharge from the hospital compared to opioid medications for postoperative pain following URS and stent placement. The objective of this study will be to compare the pain control effects of no opioid and opioid pain killers during the post-operative period. This study will be a Randomized Clinical trial. Data will be collected from department of Urology, PKLI, Lahore. All patients included in this study will undergo ureteroscopic laser lithotripsy of ureter stones. One group will receive tramadol (opioid) while other two groups will receive Paracetamol and diclofenac sodium (NSAIDs) respectively. All subjects will receive one of the three pain killers after ureteroscopy procedure for ureter stones in a randomized fashion. Postoperative pain intensity will be measured by the investigator and the nurse in the first hour after the surgery in the recovery room and then in urology ward at 1,6, 12, 24, 48, \& 72 hours using the Numeric Pain Intensity Scale (NPIS).A mean pain score of less than 2 for each category of surgical procedures or analgesics group will be defined as satisfactory pain control. The data will be analyzed using SPSS v 24.
Details
| Lead sponsor | Pakistan Kidney and Liver Institute and Research Center |
|---|---|
| Phase | NA |
| Status | UNKNOWN |
| Enrolment | 176 |
| Start date | 2022-08-01 |
| Completion | 2022-12 |
Conditions
- Post Operative Pain
- Ureteroscopy
- Ureter Stone
Interventions
- Opioid
- Non-Opioid Analgesic
- Non-Opioid
Primary outcomes
- Pain score in post op period at 1 hour. — [1 hour]
Pain score assessment at one hour by utilizing the Numeric Pain Intensity Scale (NPIS), score will be between 0-10. - Pain score in post op period at 6 hour. — [6 hour]
Pain score assessment at six hour by utilizing the Numeric Pain Intensity Scale (NPIS), score will be between 0-10. - Pain score in post op period at 12 hour. — [12 hour]
Pain score assessment at twelve hour by utilizing the Numeric Pain Intensity Scale (NPIS), score will be between 0-10. - Pain score in post op period at 24 hour. — [24 hour]
Pain score assessment at twenty four hour by utilizing the Numeric Pain Intensity Scale (NPIS), score will be between 0-10. - Pain score in post op period at 48 hour. — [48 hour]
Pain score assessment at forty eight hour by utilizing the Numeric Pain Intensity Scale (NPIS), score will be between 0-10. - Pain score in post op period at 72 hour. — [72 hour]
Pain score assessment at seventy two hour by utilizing the Numeric Pain Intensity Scale (NPIS), score will be between 0-10.
Countries
Pakistan