NCT05504629

Interindividual Postexercise Hypotension Response in Morbid Obesity

Completed NA Last updated 24 August 2022

What this trial tests

NA trial testing Concurrent training order 1 in Metabolic Syndrome in 40 participants. Completed in 5 October 2019.

Timeline

5 March 2019

Primary endpoint
5 September 2019

5 October 2019

Quick facts

Lead sponsor	Universidad Nacional Andres Bello
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	crossover
Masking	single
Primary purpose	treatment
Enrollment	40
Start date	5 March 2019
Primary completion	5 September 2019
Estimated completion	5 October 2019
Sites	1 location across Chile

Drugs / interventions tested

• Concurrent training order 1
• RT+ET

Conditions studied

• Metabolic Syndrome — all drugs for Metabolic Syndrome →
• Morbid Obesity — all drugs for Morbid Obesity →

Sponsor

Universidad Nacional Andres Bello

Who can join

Adults 18 to 59, any sex, with Metabolic Syndrome or Morbid Obesity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A quasi-experimental study developed in sedentary morbidly obese men and women (age 43.6±11.3 y; body mass index \[BMI\] ≥40 kg/m2) were assigned to a CT group of ET plus RT (ET+RT; n=19; BMI 47.8±16.7) or RT plus ET order group (RT+ET; n=17; BMI 43.0±8.0). Subjects of both groups received eight exercise sessions over four weeks. Systolic (SBP), diastolic (DBP), mean arterial pressure \[MAP\], heart rate at rest \[HR\], and pulse pressure \[PP\] measurements before and after 10 minutes postexercise. Secondary outcomes were other anthropometric, body composition, metabolic, and physical condition parameters. Using the ∆SBP reduction, and quartile categorization (Q) in 'high' (Rs: quartile 4), 'moderate' (MRs: quartile 3), 'low' (LRs: quartile 2), and 'nonresponders' (NRs: quartile 1) were reported.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Characterizing the interindividual postexercise hypotension response for two order groups of concurrent training in patients with morbid obesity.
   Álvarez C, Guede-Rojas F, Ramírez-Campillo R, Andrade DC, et al · · 2022 · cited 4× · PMID 36299263 · DOI 10.3389/fphys.2022.913645