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NCT05500976: Mini-MED
Metabolomics Initiative: Mediterranean-amplified vs Habitual Western Diet on Food Signatures, Health, and Microbiome
NA trial testing Semi-controlled dietary intervention - Western in Dietary Habits in 22 participants. Participants enrolled and being followed up; not accepting new ones.
31 March 2025
Quick facts
| Lead sponsor | University of Colorado, Denver |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 22 |
| Start date | 21 November 2022 |
| Primary completion | 31 March 2025 |
| Estimated completion | 31 March 2025 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Semi-controlled dietary intervention - Western
- Semi-controlled dietary intervention - MiniMed
Conditions studied
- Dietary Habits — all drugs for Dietary Habits →
Sponsor
University of Colorado, Denver
Who can join
Adults 30 to 69, any sex, with Dietary Habits. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study plans to learn more about how consuming a diet with foods typical to a Mediterranean Diet such as whole grains, fruits and vegetables in a Western-style diet compares to eating a typical Western-style diet. This study will look at how diet affects overall health including risk factors for heart disease, gut health and inflammation as well as underlying mechanisms linking whole food to health. Findings from this study will potentially inform effective dietary recommendations and interventions, thereby reducing chronic disease in humans.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Salmon Food-Specific Compounds and Their Metabolites Increase in Human Plasma and Are Associated with Cardiometabolic Health Indicators Following a Mediterranean-Style Diet Intervention.
Hill EB, Reisdorph RM, Rasolofomanana-Rajery S, Michel C, et al · · 2024 · cited 4× · PMID 37918675 · DOI 10.1016/j.tjnut.2023.10.024 -
mini-MED: study protocol for a randomized, multi-intervention, semi-controlled feeding trial of a Mediterranean-amplified vs. habitual Western dietary pattern for the evaluation of food-specific compounds and cardiometabolic health.
Hill EB, Tang M, Long JM, Kemp JF, et al · · 2024 · cited 2× · PMID 38302990 · DOI 10.1186/s13063-024-07939-8
Verify or expand the search:
- PubMed search for NCT05500976
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Dietary Habits
Currently open trials in the same condition.
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- NCT05862818 — Can Food Timing Reduce Your Diabetes Risk? · NA · recruiting
- NCT06912425 — Effects of an Exercise and Diet Program on Biochemistry and Body Composition in Patients With CKD in G1 and G2 Stages · NA · recruiting
Other University of Colorado, Denver trials
Trials by the same sponsor.
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- NCT07453732 — Banana Leaves as a Wound Dressing for Partial Thickness Second Degree Burns in Adult Patients. · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05500976 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Colorado, Denver
- Last refreshed: 27 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05500976.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing