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NCT05499559

Effects of 12-week Digital Treatment in Patients With Hand OA on Pain and Function

Completed Results posted Last updated 27 August 2025
What this trial tests

trial testing Joint Academy digital treatment in Hand Osteoarthritis in 846 participants. Completed in 26 June 2023.

Timeline
7 July 2021
Primary endpoint
31 July 2022
26 June 2023

Quick facts

Lead sponsorJoint Academy
StatusCompleted
Study typeOBSERVATIONAL
Enrollment846
Start date7 July 2021
Primary completion31 July 2022
Estimated completion26 June 2023
Sites1 location across Sweden

Drugs / interventions tested

Conditions studied

Sponsor

Joint Academy

Who can join

18 and older, any sex, with Hand Osteoarthritis or Wrist Osteoarthritis. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Change in Pain Intensity (Numerical Rating Scale NRS, Discrete Boxes 0-10, Higher Score Mean Worse Pain) Primary · Change in pain intensity from baseline to 3 months of treatment.

Pain intensity was assessed using the Numerical Rating Scale (NRS, discrete boxes 0-10) with the instruction: "Mark on this scale how much pain you had in your hand over the past week." The NRS ranged from 0, representing no pain, to 10, representing the maximum pain imaginable. A higher score indicated greater pain intensity. Participants completed mandatory self-assessment questionnaires at baseline and again at 3 months of treatment. All responses were self-reported and entered directly via the digital program interface.

GroupValue95% CI
Joint Academy-1.30-1.49 – -1.12
Functional Index for Hand OsteoArthritis (FIHOA 0 - 30 Higher Score Means Worse Outcome) Secondary · Change of Functional Index for Hand OsteoArthritis-score between baseline to 3 months of treatment

The FIHOA is a 10-item questionnaire based on a semi-quantitative assessment scoring the disease on a 4-point scale with a total scoring from 0 to 30 where a higher score equals more functional impairments. The FIHOA has been shown to be valid, sensitive, clinically relevant for the population and shown consistency and acceptable reliability. The literature also suggests it is associated with pain, muscle strength and health related quality of life in people with hand OA. All outcomes were self-assessed and self-entered using the digital program interface.

GroupValue95% CI
Joint Academy-0.81-1.02 – -0.60
Analgesic Use Secondary · Reduction in the number of participants using analgesics from baseline to the 3-month follow-up.

Analgesic use was assessed with the question: "In the past month, have you taken any medication for the pain in your hand?" (response options: Yes or No). This measure represents the absolute count of participants who reported a decrease in analgesic use from baseline to the 3-month follow-up (saying Yes at baseline but No at follow up.

GroupValue95% CI
Joint Academy22
Willingness for Surgery Secondary · Reduction in the number of participants wanting to undergo surgery from baseline to the 3-month follow-up.

Question: "Based on your symptoms, are you considering to undergo surgery of your hand?" Options: "No, I'm not; Yes, I'm considering surgery but it's not yet scheduled; Yes, surgery is scheduled; Surgery has been performed (only asked at follow up); I don't know" This measure represents the absolute count of participants reporting reduced willingness to undergo surgery from baseline to the 3-month follow-up.

GroupValue95% CI
Joint Academy5
Fear of Physical Activity Secondary · Reduction in the number of participants responding "yes" from baseline to the 3-month follow-up.

Fear of physical activity was assessed with the question: "Are you concerned that your finger joints may be damaged by physical activity or exercise?" (response options: Yes or No). This measure represents the absolute count of participants reporting a reduction in fear of physical activity from baseline to the 3-month follow-up.

GroupValue95% CI
Joint Academy17
Stiffness in Affected Joint (NRS, 0-10, Higher Score Mean Worse Outcome) Secondary · At baseline and 3 months

Question "Mark on the scale how much stiffness you have felt in your left/right hand due to your osteoarthritis during the past week" with a NRS ranging from 0 (none) to 10 (extreme stiffness) where a higher score equals more stiffness

GroupValue95% CI
Joint Academy-0.81-1.02 – -0.60
Received Injection at the Affected Joint (Yes/no) Secondary · Reduction in the number of participants answering "yes" between baseline and 3 month follow up

In the past month, have you received an injection in your "index joint" for the pain?

GroupValue95% CI
Joint Academy17

Sponsor's own description

The purpose of this study is to evaluate the effect of a 12 week digital treatment program for patients with hand osteoarthritis. The treatment consisted of exercises and educational sessions with respect to the disease, its natural course and recommended treatment strategies. Design: An observational longitudinal cohort study. The investigators will include participants who participated in the digital treatment of Joint Academy® for 3 months. Outcomes: Investigators will analyze pain with Numeric Rating Scale (NRS) 0-10 (best to worst), function with the Functional Index for Hand OsteoArthritis (FIHOA) and health related quality of life with EuroQol-5 Dimensions-5 Levels (EQ-5D-5L) at baseline and at 3 months. Main outcome will be change in pain. The investigators will also analyze minimally clinical important changes (improved or not) and mean changes in EQ-5D-5L index score, pain and function.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other recruiting trials for Hand Osteoarthritis

Currently open trials in the same condition.

Other Joint Academy trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05499559.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing