Adults 18 to 30, any sex, with Cigarette Smoking Behavior. Patients with the condition only — healthy volunteers not accepted.
Results — posted to ClinicalTrials.gov
Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.
Intention to Quit Smoking at Follow-upPrimary· Day [0] reported for No-message, single-message immediate, & 3-messages immediate conditions; Week [1] reported for Single-message & 3-messages 1-week delay conditions; Month [1] reported for Single-message & 3-messages 1-month delay conditions
We used a 4-item scale on intention to quit smoking at baseline and at follow-up (immediate, one-week and one-month) among current smokers only:
1. I will make an effort to quit smoking in the next 30 days;
2. I intend to quit smoking in the next 30 days;
3. I expect to quit smoking in the next 30 days;
4. How likely is it that you will quit smoking in the next 30 days. Responses ranged on 7-point Likert-like scales. Responses were summed to create a scale for intention to quit (range from 4-28), higher scores indicate higher intention to quit.
Group
Value
95% CI
Currently Smoking, Single Message 1 Week Delay
11.8
± 8.5
Currently Smoking, Single Message 1 Month Delay
11.0
± 9.0
Currently Smoking, Single Message 1 Month Delay, Repeated Exposure
14.4
± 8.1
Currently Smoking, Three Messages 1 Week Delay
9.9
± 7.8
Currently Smoking, Three Messages 1 Month Delay
11.1
± 8.4
Currently Smoking, Three Messages 1 Month Delay Repeat Exposure
14.4
± 7.9
Intention to Purchase CigarettesPrimary· Day [0] reported for No-message, single-message immediate, & 3-messages immediate conditions; Week [1] reported for Single-message & 3-messages 1-week delay conditions; Month [1] reported for Single-message & 3-messages 1-month delay conditions
The Juster scale was used to measure intention to purchase cigarettes at baseline and at one-month follow-up.
Participants were asked, "How likely are you to purchase cigarettes in the next 6 months?" Responses ranged from 0=No chance, almost no chance (1 in 100) to 10=Certain, practically certain (99 in 100).
Higher values reflect higher intention to purchase.
Group
Value
95% CI
Currently Smoking, Single Message 1 Week Delay
5.5
± 3.8
Currently Smoking, Single Message 1 Month Delay
5.7
± 3.7
Currently Smoking, Single Message 1 Month Delay, Repeated Exposure
4.2
± 3.8
Currently Smoking, Three Messages 1 Week Delay
5.9
± 3.3
Currently Smoking, Three Messages 1 Month Delay
5.7
± 3.5
Currently Smoking, Three Messages 1 Month Delay Repeat Exposure
3.9
± 3.4
Not Currently Smoking, Single Message 1 Week Delay
0.4
± 1.4
Not Currently Smoking, Single Message 1 Month Delay
0.2
± 0.5
Not Currently Smoking, Single Message 1 Month Delay, Repeated Exposure
0.4
± 1.2
Not Currently Smoking, Three Messages 1 Week Delay
0.2
± 0.5
Not Currently Smoking, Three Messages 1 Month Delay
0.3
± 1.1
Not Currently Smoking, Three Messages 1 Month Delay Repeat Exposure
0.4
± 1.3
Susceptibility to Smoke CigarettesPrimary· Day [0] reported for No-message, single-message immediate, & 3-messages immediate conditions; Week [1] reported for Single-message & 3-messages 1-week delay conditions; Month [1] reported for Single-message & 3-messages 1-month delay conditions
Susceptibility to smoke cigarettes were measured using four-items:
1. Have you ever been curious about smoking a cigarette?
2. Do you think you will smoke a cigarette in the next year?
3. Do you think that you will try a cigarette soon?
4. If one of your best friends were to offer you a cigarette, would you smoke it? Responses ranged on 4-point Likert-like scales.
Responses were summed to create a scale for susceptibility to smoke cigarettes (range from 0-12). This was only measured among participants who did not currently smoke.
Higher scores indicate increased susceptibility to smoke ciga
Group
Value
95% CI
Not Currently Smoking, No Message Condition
3.0
± 2.6
Not Currently Smoking, Single Message Immediate
2.7
± 2.4
Not Currently Smoking, Single Message 1 Week Delay
2.2
± 2.7
Not Currently Smoking, Single Message 1 Month Delay
2.8
± 2.5
Not Currently Smoking, Single Message 1 Month Delay, Repeated Exposure
2.5
± 2.7
Not Currently Smoking, Three Messages Immediate
3.0
± 2.9
Not Currently Smoking, Three Messages 1 Week Delay
1.9
± 2.8
Not Currently Smoking, Three Messages 1 Month Delay
2.6
± 2.6
Not Currently Smoking, Three Messages 1 Month Delay Repeat Exposure
2.8
± 3.0
Receptivity to MarketingSecondary· Day [0] reported for No-message, single-message immediate, & 3-messages immediate conditions; Week [1] reported for Single-message & 3-messages 1-week delay conditions; Month [1] reported for Single-message & 3-messages 1-month delay conditions
Receptivity to marketing was measured using 2 items:
1. Tobacco companies should have the same rights to advertise as other companies.
2. Are you open to using or wearing something with a tobacco company logo or picture on it? Response options range from 1 (strongly agree) to 5 (strongly disagree)
The scale is a sum of the responses to these items, the scale ranges from 2 to 10, with lower scores indicating greater receptivity to marketing.
Group
Value
95% CI
Currently Smoking, No Message Condition
6.3
± 2.5
Currently Smoking, Single Message Immediate
6.1
± 2.6
Currently Smoking, Single Message 1 Week Delay
6.4
± 2.5
Currently Smoking, Single Message 1 Month Delay
6.6
± 2.5
Currently Smoking, Single Message 1 Month Delay, Repeated Exposure
6.8
± 2.4
Currently Smoking, Three Messages Immediate
6.5
± 2.5
Currently Smoking, Three Messages 1 Week Delay
6.7
± 2.6
Currently Smoking, Three Messages 1 Month Delay
6.3
± 2.6
Currently Smoking, Three Messages 1 Month Delay Repeat Exposure
7.2
± 2.5
Not Currently Smoking, No Message Condition
8.3
± 1.7
Not Currently Smoking, Single Message Immediate
8.5
± 1.5
Not Currently Smoking, Single Message 1 Week Delay
8.4
± 1.5
Tobacco Industry AttitudesSecondary· Day [0] reported for No-message, single-message immediate, & 3-messages immediate conditions; Week [1] reported for Single-message & 3-messages 1-week delay conditions; Month [1] reported for Single-message & 3-messages 1-month delay conditions
Tobacco industry attitudes were measured using 3 items:
1. I would like to see cigarette companies go out of business.
2. I would not work for a cigarette company.
3. How much do you like cigarette companies.
Response options for items 1 and 2 were from 1 (Strongly agree) to 5 (Strongly disagree). Response options for item 3 were from 1 (Dislike strongly) to 5 (Like strongly). Response options were summed across these 3 items to create the tobacco industry attitudes scale.
Values range from 3 to 15, with lower scores indicating stronger anti-industry sentiment.
Group
Value
95% CI
Currently Smoking, No Message Condition
8.1
± 3.4
Currently Smoking, Single Message Immediate
8.2
± 3.4
Currently Smoking, Single Message 1 Week Delay
7.8
± 3.4
Currently Smoking, Single Message 1 Month Delay
7.6
± 3.5
Currently Smoking, Single Message 1 Month Delay, Repeated Exposure
7.1
± 2.8
Currently Smoking, Three Messages Immediate
7.4
± 3.5
Currently Smoking, Three Messages 1 Week Delay
8.0
± 3.3
Currently Smoking, Three Messages 1 Month Delay
7.8
± 3.3
Currently Smoking, Three Messages 1 Month Delay Repeat Exposure
6.7
± 3.2
Not Currently Smoking, No Message Condition
5.0
± 2.2
Not Currently Smoking, Single Message Immediate
4.8
± 1.8
Not Currently Smoking, Single Message 1 Week Delay
4.5
± 1.8
Tobacco Industry BeliefsSecondary· Day [0] reported for No-message, single-message immediate, & 3-messages immediate conditions; Week [1] reported for Single-message & 3-messages 1-week delay conditions; Month [1] reported for Single-message & 3-messages 1-month delay conditions
Industry beliefs were measured using 4 items:
Cigarette companies lie. Cigarette companies target teens to replace smokers who die. Cigarette companies deny that cigarettes cause cancer and other harmful diseases.
Cigarette companies deny that cigarettes are addictive.
Response options were from 1 (Strongly agree) to 5 (Strongly disagree).
Responses were summed across these 4 items to create the tobacco industry beliefs scale. Values ranges from 4 to 20, with lower scores indicating stronger anti-industry sentiment.
Group
Value
95% CI
Currently Smoking, No Message Condition
11.7
± 4.5
Currently Smoking, Single Message Immediate
11.7
± 4.9
Currently Smoking, Single Message 1 Week Delay
10.9
± 4.4
Currently Smoking, Single Message 1 Month Delay
11.1
± 4.7
Currently Smoking, Single Message 1 Month Delay, Repeated Exposure
10.4
± 4.3
Currently Smoking, Three Messages Immediate
11.0
± 4.2
Currently Smoking, Three Messages 1 Week Delay
11.4
± 4.0
Currently Smoking, Three Messages 1 Month Delay
10.5
± 4.5
Currently Smoking, Three Messages 1 Month Delay Repeat Exposure
10.5
± 4.4
Not Currently Smoking, No Message Condition
8.9
± 3.7
Not Currently Smoking, Single Message Immediate
8.3
± 3.5
Not Currently Smoking, Single Message 1 Week Delay
8.9
± 3.5
Sponsor's own description
Project RESIST is an R01 study funded by NCI focused on determining the effects of using culturally tailored inoculation approaches to increase resilience to tobacco marketing influences among young adult sexual minority women ages 18-30 and incorporates critical stakeholder inputs that support later adoption and implementation. The study team is utilizing formative research to design and pre-test anti-smoking messages and two national longitudinal online survey experiments.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
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Sponsor: as reported to ClinicalTrials.gov by Abramson Cancer Center at Penn Medicine
Last refreshed: 31 July 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05499520.