NCT05497960

Vivo Prediabetes Study: Online, Live, and Interactive Strength Training for Older Adults With Prediabetes

Completed NA Results posted Last updated 16 September 2025

What this trial tests

NA trial testing Vivo workout in PreDiabetes in 28 participants. Completed in 15 May 2023.

Timeline

1 September 2022

Primary endpoint
31 March 2023

15 May 2023

Quick facts

Lead sponsor	Eric Levian
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	prevention
Enrollment	28
Start date	1 September 2022
Primary completion	31 March 2023
Estimated completion	15 May 2023
Sites	1 location across United States

Drugs / interventions tested

• Vivo workout

Conditions studied

• PreDiabetes — all drugs for PreDiabetes →
• Older Adults — all drugs for Older Adults →
• Muscle Loss — all drugs for Muscle Loss →
• Muscle Weakness — all drugs for Muscle Weakness →

Sponsor

Eric Levian

Who can join

60 and older, any sex, with PreDiabetes or Older Adults. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Leg Strength Assessed Through a 30 Second Chair Rise Test Primary · at 3 months (endpoint)

Participants completed as many chair stands as they could in 30 seconds

Group	Value	95% CI
Vivo Strength Training	14.2	± 2.9

Workout Attendance Primary · after each workout session for up to 3 months (endpoint)

Attendance to each workout session was tallied. A possible 24 workout sessions were offered for the intervention (12 weeks of 2 days a week for workouts). The number of participants includes everyone who completed intervention, excluding those who stopped intervention at some point. The data reported represents the overall percent attendance of the participants that completed the intervention (N=22 participants). Attendance was calculated by averaging the number of sessions attended divided by the total number of exercise sessions attended (24 sessions).

Group	Value	95% CI
Vivo Strength Training	85	0 – 100

Intervention Engagement Assessed by Self- Reported Ease of Use Primary · at 3 months (endpoint)

Participants completed a questionnaire (Likert Scale) on their experience using Vivo. 1= Strong Disagree to 5= Strongly Agree

Easy to sign into class

Group	Value	95% CI
Vivo Strength Training	82

Easy to follow workout instructions during class

Group	Value	95% CI
Vivo Strength Training	86

Level system made it easy to tailor intensity and exercises to my abilities

Group	Value	95% CI
Vivo Strength Training	95

Program Satisfaction Primary · at the 3 month (endpoint)

Participants completed the question on a questionnaire to answer "What was your overall satisfaction with Vivo?" Responses are percentage of participant who reported being satisfied or very satisfied with the Vivo intervention. A higher number indicates higher satisfaction.

Group	Value	95% CI
Vivo Strength Training	95

Exercise Intervention Trainer Fidelity Checklist Primary · over the course of the 12 week intervention

The exercise intervention fidelity as assessed at 4 time points over the course of the 12-week exercise program using a 9-item checklist to ensure unbiased assessment. The purpose was to observe the exercise session to see if the main areas of the intervention were being delivered; workout intensity, safety, and participation and engagement. The results below indicate the percentage of exercise workouts that met the 9-item checklist. A higher score indicates higher fidelity.

Group	Value	95% CI
Vivo Strength Training	96

Adverse events — posted to ClinicalTrials.gov

Time frame: Adverse event data was collected for each participant from enrollment to study completion or study withdraw. The duration of participation in the study was approximately 12 weeks.. Reporting threshold: 5%. Adverse-event reports describe events observed during the trial — not all are caused by the drug.

Vivo Intervention

Serious: 0/22 (0%)

Deaths: 0/22

Other adverse events (3 terms — click to expand)

Reaction	System	Vivo Intervention
COVID infection	Infections and infestations	—
Back pain following a skiing accident	Musculoskeletal and connective tissue disorders	—
Shoulder pain following exercise	Musculoskeletal and connective tissue disorders	—

Data from ClinicalTrials.gov NCT05497960 adverse events section.

Sponsor's own description

This research trial studies the effect of an online, live and interactive strength training program on physical function and strength in older adults with prediabetes.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.