Last reviewed · How we verify
NCT05497726: IBIZA-2
Fluorescent Sentinel Lymph Node Identification in Colon Carcinoma Using Intravenous Bevacizumab-800CW
NA trial testing Sentinel lymph node detection using intravenous bevacizumab-800CW in Colorectal Neoplasms in 5 participants. Completed in 10 October 2023.
10 July 2023
Quick facts
| Lead sponsor | Meander Medical Center |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 5 |
| Start date | 27 January 2023 |
| Primary completion | 10 July 2023 |
| Estimated completion | 10 October 2023 |
| Sites | 1 location across Netherlands |
Drugs / interventions tested
- Sentinel lymph node detection using intravenous bevacizumab-800CW
Conditions studied
- Colorectal Neoplasms — all drugs for Colorectal Neoplasms →
- Colon Neoplasm — all drugs for Colon Neoplasm →
- Sentinel Lymph Node — all drugs for Sentinel Lymph Node →
- Fluorescence — all drugs for Fluorescence →
Sponsor
Meander Medical Center
Who can join
18 and older, any sex, with Colorectal Neoplasms or Colon Neoplasm. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This prospective study aims to assess the safety and feasibility of lymph node identification using bevacizumab-800CW in patients with cT1-3N0-2 tumours, using intravenous administration.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Tumour-targeted fluorescence-guided surgery in gastrointestinal cancer: A systematic review of preclinical and clinical research.
Darai A, Graus EHM, van der Stroom FJA, Rijpkema M, et al · · 2026 · PMID 41866830 · DOI 10.1002/ctm2.70615
Verify or expand the search:
- PubMed search for NCT05497726
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Meander Medical Center trials
Trials by the same sponsor.
- NCT06652672 — Sentinel Node and Organ-sparing Surgery in Stage I Colon Carcinoma · NA · recruiting
- NCT06430931 — Biological OviTex Versus Synthetic Graft in Robotic Prolapse Surgery · NA · recruiting
- NCT05498051 — Fluorescent Sentinel Lymph Node Identification in Colon Carcinoma Using Submucosal Bevacizumab-800CW. · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05497726 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Meander Medical Center
- Last refreshed: 7 November 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05497726.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing