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NCT05496452
Beta-lactoglobulin, Immobilisation and Muscle Protein Synthesis
NA trial testing Beta-lactoglobulin in Muscle Atrophy in 24 participants. Status unknown.
1 March 2024
Quick facts
| Lead sponsor | King's College London |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 24 |
| Start date | 1 April 2023 |
| Primary completion | 1 March 2024 |
| Estimated completion | 1 August 2024 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Beta-lactoglobulin
- Carbohydrate — full drug profile →
Conditions studied
- Muscle Atrophy — all drugs for Muscle Atrophy →
Sponsor
King's College London
Who can join
Adults 18 to 45, any sex, with Muscle Atrophy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The objectives of this study are to: 1. Establish whether combined β-lactoglobulin supplementation and resistance training for 1 week prior to 5 days of limb immobilisation will attenuate the decrease in integrated free-living rates of MPS during short-term muscle disuse. 2. Establish whether combined β-lactoglobulin supplementation and resistance training for 1 week prior to limb immobilisation will attenuate the decrease in muscle mass and strength during short-term muscle disuse.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
The effect of combined β-lactoglobulin supplementation and resistance exercise training prior to limb immobilisation on muscle protein synthesis rates in healthy young adults: study protocol for a randomised controlled trial.
Hughes A, Francis T, Marjoram L, Rooney JH, et al · · 2023 · PMID 37312095 · DOI 10.1186/s13063-023-07329-6 -
The effect of combined β-lactoglobulin supplementation and resistance exercise training prior to limb immobilisation on muscle protein synthesis rates in healthy young adults: study protocol for a randomised controlled trial
Hughes A, Francis T, Marjoram L, Rooney J, et al · · 2023 · DOI 10.21203/rs.3.rs-2573935/v1
Verify or expand the search:
- PubMed search for NCT05496452
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05496452 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by King's College London
- Last refreshed: 26 April 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05496452.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing