NCT05495841 is a clinical trial of Pre-oxygenation in Surgery, sponsored by Beth Israel Deaconess Medical Center.

Who is sponsoring NCT05495841?

NCT05495841 is sponsored by Beth Israel Deaconess Medical Center.

What drugs are being tested in NCT05495841?

Interventions in NCT05495841: Pre-oxygenation.

Is NCT05495841 still recruiting?

NCT05495841 is currently completed. Last updated 30 November 2023.

Last reviewed 2023-11-30 · How we verify

NCT05495841

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

OPTiMASK: Comparison of Pre-oxygenation With Standard Face Mask Combined With High Flow Nasal Oxygen With Pre-oxygenation With Standard Face Mask Alone

Completed Last updated 30 November 2023

What this trial tests

trial testing Pre-oxygenation in Surgery in 80 participants. Completed in 30 June 2023.

Timeline

18 August 2022

Primary endpoint
30 June 2023

30 June 2023

Quick facts

Lead sponsor	Beth Israel Deaconess Medical Center
Status	Completed
Study type	OBSERVATIONAL
Enrollment	80
Start date	18 August 2022
Primary completion	30 June 2023
Estimated completion	30 June 2023
Sites	1 location across United States

Drugs / interventions tested

Pre-oxygenation

Conditions studied

Surgery — all drugs for Surgery →

Sponsor

Beth Israel Deaconess Medical Center

Who can join

18 and older, any sex, with Surgery. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is an observational, prospective study of patients undergoing a surgical procedure. Three parallel studies are taking place with collaborators in other countries. This study aims to bring novel insights regarding the benefits of pre-oxygenation combining standard oxygen facemask with high-flow nasal oxygen (HFNO), as opposed to standard oxygen facemask alone by assessing end-tidal oxygen (ETO2) levels after intubation.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Preoxygenation with standard facemask combining apnoeic oxygenation using high flow nasal cannula versuss standard facemask alone in patients with and without obesity: the OPTIMASK international study.
Jaber S, De Jong A, Schaefer MS, Zhang J, et al · · 2023 · cited 9× · PMID 37014462 · DOI 10.1186/s13613-023-01124-x

Verify or expand the search:

Other trials of Pre-oxygenation

Trials testing the same drug.

NCT04767867 — Pre-oxygenation With Facemask Oxygen vs High-flow Nasal Oxygen vs High-flow Nasal Oxygen Plus Mouthpiece Oxygen · NA · completed

Other recruiting trials for Surgery

Currently open trials in the same condition.

NCT07369921 — Pediatric Pilonidal Sinus Surgical Treatment · NA · recruiting
NCT07362303 — Neuralert Stroke Monitor Trial · NA · recruiting
NCT07404163 — Walkway Used in Postoperative Mobilization · NA · active not recruiting
NCT07218289 — Green Light for Post-Operative Wellness · NA · recruiting
NCT07342751 — The Effect of Listening to Music During Mobilization on Pain and Fear in Children Undergoing Abdominal Surgery · NA · active not recruiting

Other Beth Israel Deaconess Medical Center trials

Trials by the same sponsor.

NCT07352657 — Remote Alert Pathway To Optimize CaRe of Cardiac Implantable Electrical Devices: The RAPTOR-CIED Study (Main Phase) · NA · not yet recruiting
NCT07531602 — Effect of PEEP on Cardiac Function · NA · not yet recruiting
NCT07534683 — Primed to Thrive: Investigating the Combined Impact of Mindfulness Education and Meditation Practice on Psychological an · NA · not yet recruiting
NCT07277244 — Low-Intensity Mechanical Ventilation in the Operating Room: a Pilot Study · NA · enrolling by invitation
NCT06896474 — SDM POSSIBLE: A Breast Cancer Treatment Decision Aid for Women 70+ With Low-Risk Stage I Breast Cancers · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05495841 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Beth Israel Deaconess Medical Center
Last refreshed: 30 November 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05495841.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing