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NCT05494216
Advanced Sperm Selection Techniques and Their Contribution to Blastocyst Euploidy Rates
NA trial testing PICSI in Sperm DNA Fragmentation in 515 participants. Completed in 1 January 2024.
1 January 2024
Quick facts
| Lead sponsor | Ganin Fertility Center |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 515 |
| Start date | 1 August 2022 |
| Primary completion | 1 January 2024 |
| Estimated completion | 1 January 2024 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- PICSI
- MACS
Conditions studied
- Sperm DNA Fragmentation — all drugs for Sperm DNA Fragmentation →
- Infertility — all drugs for Infertility →
Sponsor
Ganin Fertility Center
Who can join
Adults 18 to 50, any sex, with Sperm DNA Fragmentation or Infertility. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Comparing different advanced sperm selection techniques like Physiological ICSI (PICSI) and magnetic activated cell sorting (MACS) in terms of the PGT-A outcomes of each arm blastocysts
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05494216
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of PICSI
Trials testing the same drug.
- NCT06602687 — PICSI Impact on Euploidy in Assisted Reproduction · NA · recruiting
- NCT05762770 — A Trial of Sperm Injection (PICSI) on Miscarriage Rates in Assisted Conception · NA · unknown
- NCT04496232 — Strategies for Reducing Sperm DNA Fragmentation in ICSI Semen Samples: a Prospective Randomized Controlled Trial · NA · completed
- NCT03360526 — What is the Best Sperm Source and Way of Sperm Selection in Cases With Abnormal sORP Levels on the Day of ICSI? · NA · unknown
- NCT03398317 — Sperm Selection by Either PICSI or MACS in Cases With Abnormal Sperm DNA Fragmentation Index for ICSI · NA · completed
Other Ganin Fertility Center trials
Trials by the same sponsor.
- NCT06850909 — Evaluating the Influence of 3D Culture Dish Design on Preimplantation Genetic Development in Sibling Oocytes: a Randomiz · NA · not yet recruiting
- NCT06476379 — Can the Origin of Sperm Affect Embryo Ploidy in Patients With Severe Male Factor Infertility? · NA · completed
- NCT06231589 — PGT-A Evaluates Advanced Sperm Selection in Embryos From High Teratozoospermia Males · NA · completed
- NCT05499988 — The Importance of Blastocyst Diamater and Its Correlation to Reproductive Outcomes in PGT-A Cases · unknown
- NCT04496232 — Strategies for Reducing Sperm DNA Fragmentation in ICSI Semen Samples: a Prospective Randomized Controlled Trial · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05494216 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ganin Fertility Center
- Last refreshed: 7 May 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05494216.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing