NCT05493254 (E-STOP) is a NA clinical trial of Smoking cessation e-visit in Smoking Cessation, sponsored by Medical University of South Carolina.

Who is sponsoring NCT05493254?

NCT05493254 is sponsored by Medical University of South Carolina.

What drugs are being tested in NCT05493254?

Interventions in NCT05493254: Smoking cessation e-visit, Treatment As Usual.

What condition does NCT05493254 study?

NCT05493254 studies Smoking Cessation.

Is NCT05493254 still recruiting?

NCT05493254 is currently recruiting now. Last updated 5 March 2026.

Last reviewed 2026-03-05 · How we verify

NCT05493254: E-STOP

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Enhancing Smoking Cessation Via Telehealth Options in Primary Care

Recruiting now NA Last updated 5 March 2026

What this trial tests

NA trial testing Smoking cessation e-visit in Smoking Cessation in 672 participants. Currently enrolling.

Timeline

31 August 2022

Primary endpoint
31 December 2026

31 December 2026

Quick facts

Lead sponsor	Medical University of South Carolina
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	health services research
Enrollment	672
Start date	31 August 2022
Primary completion	31 December 2026
Estimated completion	31 December 2026
Sites	1 location across United States

Drugs / interventions tested

Smoking cessation e-visit
Treatment As Usual

Conditions studied

Smoking Cessation — all drugs for Smoking Cessation →

Sponsor

Medical University of South Carolina

Who can join

18 and older, any sex, with Smoking Cessation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this research study is to evaluate an electronic visit (e-visit) for smoking cessation. Participants will be randomly assigned to receive either the smoking cessation e-visit or not. The e-visit will look similar to an online questionnaire asking about smoking history, motivation to quit, and preferences for medications for quitting smoking. Participants may receive a prescription for a smoking cessation medication as an outcome of the e-visit, if randomized to the e-visit group, but there is no requirement to take any medication. This study consists of questionnaires and breath samples provided at 4 separate time points throughout the study. Participation in this study will take about 24 weeks.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Rationale, design, and protocol for a hybrid type 1 effectiveness-implementation trial of a proactive smoking cessation electronic visit for scalable delivery via primary care: the E-STOP trial.
Fahey MC, Wahlquist AE, Diaz VA, Player MS, et al · · 2023 · cited 1× · PMID 38030991 · DOI 10.1186/s12875-023-02205-3

Verify or expand the search:

Other trials of Smoking cessation e-visit

Trials testing the same drug.

NCT05764759 — Investigating Novel Smoking Cessation Primary Care Interventions in Rural Environments · NA · recruiting
NCT04316260 — Smoking Cessation E-Visit · NA · completed

Other recruiting trials for Smoking Cessation

Currently open trials in the same condition.

NCT07420621 — Preliminary Effectiveness of Enhanced Text Message + Incentives · NA · recruiting
NCT07224087 — Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients · Phase 1 · recruiting
NCT07331519 — Integrating Smoking Cessation With Low-dose CT-screening for Lung Cancer · NA · recruiting
NCT07210567 — Mindfulness-based Ecological Momentary Intervention for Smoking Cessation Among Cancer Survivors · NA · recruiting
NCT07129590 — Trauma-Informed Care for Smoking Cessation for Pregnancy · NA · recruiting

Other Medical University of South Carolina trials

Trials by the same sponsor.

NCT06491264 — Multiparameter Optimized tES for Memory in Aging · NA · withdrawn
NCT07513389 — Omission of Postoperative Radiation in HPV-Associated Oropharyngeal Cancer Using ctHPVDNA Surveillance (OPERATION) · Phase 2 · not yet recruiting
NCT03101917 — Microtable® Method for Cochlear Implantation Investigational Device Exemption (IDE) · NA · not yet recruiting
NCT07149207 — Intraoperative Molecular Imaging Using ICG for Head and Neck Tumors · Phase 2 · recruiting
NCT06148038 — CBD for Breast Cancer Primary Tumors · Phase 1 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05493254 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Medical University of South Carolina
Last refreshed: 5 March 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05493254.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing