NCT05490641 (Project KNOWN) is a NA clinical trial of Glucose-based biofeedback in Cancer, sponsored by The University of Texas at Arlington.

Who is sponsoring NCT05490641?

NCT05490641 is sponsored by The University of Texas at Arlington.

What drugs are being tested in NCT05490641?

Interventions in NCT05490641: Glucose-based biofeedback, Standard feedback.

What condition does NCT05490641 study?

NCT05490641 studies Cancer, Survivorship.

Is NCT05490641 still recruiting?

NCT05490641 is currently completed. Last updated 13 February 2026.

Last reviewed 2026-02-13 · How we verify

NCT05490641: Project KNOWN

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Know and Own Your Movement-related Metrics Via Wearable Devices

Completed NA Last updated 13 February 2026

What this trial tests

NA trial testing Glucose-based biofeedback in Cancer in 60 participants. Completed in 10 December 2025.

Timeline

29 March 2023

Primary endpoint
10 December 2025

10 December 2025

Quick facts

Lead sponsor	The University of Texas at Arlington
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	supportive care
Enrollment	60
Start date	29 March 2023
Primary completion	10 December 2025
Estimated completion	10 December 2025
Sites	1 location across United States

Drugs / interventions tested

Glucose-based biofeedback
Standard feedback

Conditions studied

Cancer — all drugs for Cancer →
Survivorship — all drugs for Survivorship →

Sponsor

The University of Texas at Arlington

Who can join

18 and older, any sex, with Cancer or Survivorship. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study aims to promote daily physical activity in cancer survivors who are at high risk for type 2 diabetes (T2D) by using a personalized biological-based feedback strategy. T2D is one of the most common co-occurring conditions in cancer survivors and can worsen cancer-related health outcomes, especially in those who are insufficiently active. The investigators hypothesize that seeing the immediate impacts of exercise on their biological status will motivate cancer survivors to exercise. The investigators will use real-time data from continuous glucose monitor to demonstrate the acute impact of physical activity and measure daily activity levels using wearable trackers. As wearable sensor technology is constantly advancing, this study is the first step to exploring how researchers can use wearable sensors to help people make a direct connection between their daily behaviors and health outcomes.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Using wearable biological sensors to provide personalized feedback to motivate behavioral changes: Study protocol for a randomized controlled physical activity intervention in cancer survivors (Project KNOWN).
Liao Y, Schembre SM, Brannon GE, Pan Z, et al · · 2022 · cited 2× · PMID 36099282 · DOI 10.1371/journal.pone.0274492

Verify or expand the search:

Other recruiting trials for Cancer

Currently open trials in the same condition.

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NCT07402057 — Implementation and Evaluation of a Program Aimed at Facilitating Palliative Care Conversations · NA · recruiting
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Other The University of Texas at Arlington trials

Trials by the same sponsor.

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NCT07196436 — Asthma Intervention With Residential Ventilation and Air Cleaner (AIRVAC) Study · NA · recruiting
NCT06857877 — Arlington Aging Study · recruiting
NCT06497413 — Brain Vascular and Neurocognitive Health · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05490641 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by The University of Texas at Arlington
Last refreshed: 13 February 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05490641.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing