Who is sponsoring NCT05490459?

NCT05490459 is sponsored by Element Science, Inc..

What drugs are being tested in NCT05490459?

Interventions in NCT05490459: Jewel Patch Wearable Cardioverter Defibrillator (P-WCD).

What condition does NCT05490459 study?

NCT05490459 studies Sudden Cardiac Arrest.

Is NCT05490459 still recruiting?

NCT05490459 is currently completed. Last updated 6 January 2025.

Are results published for NCT05490459?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2025-01-06 · How we verify

NCT05490459

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Jewel Electrophysiology (EP) Lab Study

Completed NA Results posted Last updated 6 January 2025

What this trial tests

NA trial testing Jewel Patch Wearable Cardioverter Defibrillator (P-WCD) in Sudden Cardiac Arrest in 18 participants. Completed in 17 April 2024.

Timeline

27 November 2018

Primary endpoint
7 October 2021

17 April 2024

Quick facts

Lead sponsor	Element Science, Inc.
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	18
Start date	27 November 2018
Primary completion	7 October 2021
Estimated completion	17 April 2024
Sites	1 location across Czechia

Drugs / interventions tested

Jewel Patch Wearable Cardioverter Defibrillator (P-WCD)

Conditions studied

Sudden Cardiac Arrest — all drugs for Sudden Cardiac Arrest →

Sponsor

Element Science, Inc.

Who can join

18 and older, any sex, with Sudden Cardiac Arrest. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Clinical Effectiveness of the Jewel Primary · Immediately following defibrillation with the study device.

The count of participants with successful single shock terminations of life-threatening VT or VF. (The endpoint would be achieved if the lower confidence limit exceeds the performance goal of 62% using a one-sided exact lower 97.4% confidence bound at one of three testing points.)

Group	Value	95% CI
Treatment	16

Sponsor's own description

Single arm open label evaluation of the Jewel Patch Wearable Cardioverter Defibrillator (P-WCD) defibrillation waveform in adult cardiac patients.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

First human safety and effectiveness study of defibrillation with a novel patch wearable cardioverter-defibrillator.
Chovanec M, Petrů J, Hála P, Kralovec S, et al · · 2024 · cited 2× · PMID 39001864 · DOI 10.1093/europace/euae189

Verify or expand the search:

Other trials of Jewel Patch Wearable Cardioverter Defibrillator (P-WCD)

Trials testing the same drug.

NCT05201495 — The Jewel IDE Study · NA · completed

Other recruiting trials for Sudden Cardiac Arrest

Currently open trials in the same condition.

NCT06804499 — Tampere Coronary Artery Disease and Sudden Cardiac Arrest Study · recruiting
NCT07444931 — Validation of Sudden Cardiac Arrest Risk Factors in Patients With CAD · recruiting
NCT06642168 — Sudden Cardiac Arrest Related to Sport in Young and Value of the Genetic Assessment: a French Prospective Register · recruiting
NCT05135403 — ASSURE WCD Clinical Evaluation - Post Approval Study (ACE-PAS) · recruiting
NCT03493516 — Prediction of ARrhythmic Events With Positron Emission Tomography II · active not recruiting

Other Element Science, Inc. trials

Trials by the same sponsor.

NCT05201495 — The Jewel IDE Study · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05490459 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Element Science, Inc.
Last refreshed: 6 January 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05490459.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing