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NCT05488860
Piezoelectric Drived Microneedling in Treating Refractory Skin Diseases
NA trial testing Triamcinolone acetonide(scar)/5-ALA(others) in Skin Diseases in 20 participants. Status unknown.
30 June 2024
Quick facts
| Lead sponsor | Xiangya Hospital of Central South University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 30 July 2022 |
| Primary completion | 30 June 2024 |
| Estimated completion | 31 July 2024 |
| Sites | 1 location across China |
Drugs / interventions tested
- Triamcinolone acetonide(scar)/5-ALA(others) — full drug profile →
- Piezoelectric drived microneedling
- 5-ALA (a photosensitizer for photodynamic therapy). — full drug profile →
Conditions studied
- Skin Diseases — all drugs for Skin Diseases →
- Hypertrophic Scar — all drugs for Hypertrophic Scar →
- Keloid — all drugs for Keloid →
- Plantar Wart — all drugs for Plantar Wart →
Sponsor
Xiangya Hospital of Central South University
Who can join
16 and older, any sex, with Skin Diseases or Hypertrophic Scar. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Piezoelectric drived microneedling treats refractory skin disorders using hollow microneedles assisted by ultrasound. Mechanically, the injection of medicine by hollow microneedling could makes the distribution of medicine more evenly. And the addition of ultrasound technique improves the effectiveness of microneedling. Investigators plan to conduct a pilot study to investigate the efficacy of using piezoelectric drived microneedles in treating refractory skin diseases.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Trial watch: an update of clinical advances in photodynamic therapy and its immunoadjuvant properties for cancer treatment.
Penetra M, Arnaut LG, Gomes-da-Silva LC. · · 2023 · cited 36× · PMID 37346450 · DOI 10.1080/2162402x.2023.2226535 -
A piezoelectric-driven microneedle platform for skin disease therapy.
Chen Z, Liu X, Jiang Z, Wu H, et al · · 2024 · cited 13× · PMID 38680817 · DOI 10.1016/j.xinn.2024.100621 -
Current State of Clinical Trials for Keloid Management: An Analysis of Trials Registered on ClinicalTrials.gov.
Park S, Li D, Guo L, Xu X. · · 2026 · PMID 42077711 · DOI 10.7759/cureus.106243
Verify or expand the search:
- PubMed search for NCT05488860
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Skin Diseases
Currently open trials in the same condition.
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- NCT07091604 — An Observational Study to Assess Objective Skin Pigmentation Variation. · recruiting
- NCT07158879 — Skin Reactions Related to Thoracic Implantable Chamber Dressings · recruiting
- NCT06850311 — Herbal Ointment in Treating Atopic Dermatitis Topically · Phase 2, PHASE3 · recruiting
- NCT06563323 — Guselkumab in the Treatment of Adults With Pyoderma Gangrenosum (PG) · Phase 2 · recruiting
Other Xiangya Hospital of Central South University trials
Trials by the same sponsor.
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- NCT07412223 — Effect of Tegileridine on Postoperative Bowel Function Recovery in Abdominal Surgery · Phase 4 · not yet recruiting
- NCT07369960 — Repetitive Transcranial Magnetic Stimulation Combined With Language Training for Language Disorders in Children With Glo · NA · recruiting
- NCT07369999 — Effects of Butylphthalide Enhanced With Tenecteplase on Neurological Function in Mild Disabling Acute Ischemic Stroke · Phase 3 · not yet recruiting
- NCT07309913 — China Atrial Fibrillation With Complex Metabolic Disorder Cohort Study (CAME Cohort) · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05488860 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Xiangya Hospital of Central South University
- Last refreshed: 5 August 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05488860.
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