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NCT05487937
Toleriane Ultra Reno in Allergic Subjects With Skin Intolerance to Their Usual Cosmetic
trial testing Use of Toleriane Ultra to relieve face allergic skin in Allergy in 109 participants. Completed in 28 September 2021.
28 September 2021
Quick facts
| Lead sponsor | Cosmetique Active International |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 109 |
| Start date | 25 May 2021 |
| Primary completion | 28 September 2021 |
| Estimated completion | 28 September 2021 |
| Sites | 1 location across Poland |
Drugs / interventions tested
- Use of Toleriane Ultra to relieve face allergic skin
Conditions studied
- Allergy — all drugs for Allergy →
Sponsor
Cosmetique Active International — full company profile →
Who can join
16 and older, any sex, with Allergy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Sensitive skin is a subjective cutaneous hyper-reactivity to environmental factors. People report exaggerated reactions when their skin, especially on the face, is in contact with substances such as cosmetics. For this reason, Toleriane Ultra has been developed to limit the risk of allergy and relieve skin discomfort. The study aims at demonstrating that Toleriane Ultra is well tolerated in participants with allergic background and having experienced former intolerance to their cosmetic or toiletries routine, and improves skin sensitivity in such individuals. This open-labeled, multicenter study was conducted under dermatological control in Caucasian subjects above 16 years of age with an allergic background and intolerance to cosmetics lasting for at least 2 years prior to inclusion. The dermocosmetic product was to be applied on the entire face twice daily for 28 days.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Clinical Measurement of Transepidermal Water Loss.
Kundu D, Jayaraman A, Sen CK. · · 2026 · cited 4× · PMID 40476522 · DOI 10.1089/wound.2024.0148 -
A Dermocosmetic Significantly Reduces the Frequency and Intensity of Facial Skin Intolerability and Sensitivity in Subjects with Skin Intolerant to Skin Care Products and Sensitive Skin.
Kerob D, Czermanska A, Karamon EM, Moga A, et al · · 2023 · cited 1× · PMID 37456802 · DOI 10.2147/ccid.s418483
Verify or expand the search:
- PubMed search for NCT05487937
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Cosmetique Active International trials
Trials by the same sponsor.
- NCT07239726 — CLINICAL INVESTIGATION TO EVALUATE THE EFFICACY AND SAFETY OF EPILADY PROTOTYPE DEVICE FOLLOWED BY APPLICATION OF A TOPI · NA · not yet recruiting
- NCT06590779 — Benefits of a Cosmetic Anti-hair Loss in Males With Hair Loss · NA · not yet recruiting
- NCT06516224 — Anti-pigmenting Effect of a Routine of Facial Products in Subjects With Melasma · NA · not yet recruiting
- NCT07537595 — Efficacy of Cosmetic Products in Preventing Pigmentation Induced by High Energy Visible Light (HEVL) [400-450nm] · completed
- NCT06320314 — Efficacy and Tolerability of Tested Formula After 3 Months in Treatment of Facial Hyperpigmentation of 3 Origins · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05487937 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cosmetique Active International
- Last refreshed: 4 August 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05487937.
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