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NCT05487508
Efficacy of Dexamethasone to Improve Clinical Outcomes in Coronary Artery Bypass Patients
Phase 4 trial testing Dexamethasone in Coronary Artery Disease in 120 participants. Completed in 31 March 2019.
31 January 2019
Quick facts
| Lead sponsor | Indonesia University |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 120 |
| Start date | 1 July 2018 |
| Primary completion | 31 January 2019 |
| Estimated completion | 31 March 2019 |
| Sites | 1 location across Indonesia |
Drugs / interventions tested
- Dexamethasone (dexamethasone) — full drug profile →
- Normal saline
Conditions studied
- Coronary Artery Disease — all drugs for Coronary Artery Disease →
- Inflammatory Response — all drugs for Inflammatory Response →
Sponsor
Indonesia University
Who can join
Adults 18 to 75, any sex, with Coronary Artery Disease or Inflammatory Response. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a single-center, double-blind, randomized controlled clinical trial comparing four groups: placebo conventional coronary artery bypass graft (CCABG) group, dexamethasone CCABG group, placebo off-pump coronary artery bypass (OPCAB) group, and dexamethasone OPCAB group. The primary outcomes of this study is comprised of presence of arrhythmia, major adverse cardiac events (MACE), myocardial infarction, stroke, renal failure, respiratory failure, inflammation, and death. These primary outcomes were assessed during the surgery, 18 hours post surgery, every day during the hospital stay, 14 days and 30 days post surgery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05487508
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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Other Indonesia University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05487508 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Indonesia University
- Last refreshed: 4 August 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05487508.
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