NCT05486910 is a clinical trial in Acne, sponsored by Cosmetique Active International.

Who is sponsoring NCT05486910?

NCT05486910 is sponsored by Cosmetique Active International.

Is NCT05486910 still recruiting?

NCT05486910 is currently completed. Last updated 4 August 2022.

Last reviewed 2022-08-04 · How we verify

NCT05486910

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Management of Side-Effects of Anti-Acne Treatment by a Cosmetic Routine

Completed Last updated 4 August 2022

What this trial tests

trial in Acne in 44 participants. Completed in 29 July 2021.

Timeline

29 April 2021

Primary endpoint
29 July 2021

29 July 2021

Quick facts

Lead sponsor	Cosmetique Active International
Status	Completed
Study type	OBSERVATIONAL
Enrollment	44
Start date	29 April 2021
Primary completion	29 July 2021
Estimated completion	29 July 2021
Sites	1 location across Poland

Conditions studied

Acne — all drugs for Acne →

Sponsor

Cosmetique Active International — full company profile →

Who can join

12 and older, any sex, with Acne. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Retinoid-based topical acne treatment may induce local tolerance issues such as erythema, dryness, stinging and burning sensations that may reduce adherence and efficacy. The tested regimen (cream and cleanser) has been specifically developed to rebalance the skin microbiome and compensate side-effects of topical treatments (hydration, skin barrier repair) together with an action on skin imperfections and marks. This open-label study was conducted in subjects aged 12 years and over with sensitive skin (\>2 on a sensitivity composite score from 0-3) treated for at least one month with the fixed-dose gel combination and presenting with treatment-related skin intolerance.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Efficacy of Spironolactone Compared with Doxycycline in Moderate Acne in Adult Females: Results of the Multicentre, Controlled, Randomized, Double-blind Prospective and Parallel Female Acne Spironolactone vs doxyCycline Efficacy (FASCE) Study.
Dréno B, Nguyen JM, Hainaut E, Machet L, et al · · 2024 · cited 11× · PMID 38380975 · DOI 10.2340/actadv.v104.26002

Verify or expand the search:

Other recruiting trials for Acne

Currently open trials in the same condition.

NCT07366229 — Topical Application of Engineered Lactobacillus Reuteri With a Zinc Sulfate-Tannic Acid MPN Coating for Acne · Phase 2 · recruiting
NCT07013747 — Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne · Phase 1, PHASE2 · recruiting
NCT06989840 — Phase 1 Study to Evaluate the Safety, Tolerability, PK, and PD of TVB-3567 in Healthy Participants With or Without Acne · Phase 1 · recruiting
NCT07368764 — The Suitability of Tience® for Treating Acne Scars · NA · recruiting
NCT06909344 — 577-nm Diode Laser in the Treatment of Non -Inflammatory Acne · NA · recruiting

Other Cosmetique Active International trials

Trials by the same sponsor.

NCT07239726 — CLINICAL INVESTIGATION TO EVALUATE THE EFFICACY AND SAFETY OF EPILADY PROTOTYPE DEVICE FOLLOWED BY APPLICATION OF A TOPI · NA · not yet recruiting
NCT06590779 — Benefits of a Cosmetic Anti-hair Loss in Males With Hair Loss · NA · not yet recruiting
NCT06516224 — Anti-pigmenting Effect of a Routine of Facial Products in Subjects With Melasma · NA · not yet recruiting
NCT07537595 — Efficacy of Cosmetic Products in Preventing Pigmentation Induced by High Energy Visible Light (HEVL) [400-450nm] · completed
NCT06320314 — Efficacy and Tolerability of Tested Formula After 3 Months in Treatment of Facial Hyperpigmentation of 3 Origins · NA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05486910 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cosmetique Active International
Last refreshed: 4 August 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05486910.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing