Last reviewed · How we verify
NCT05484570
Natural History Study for DNA Repair Disorders
trial testing Interval History in DNA Repair Disorder in 40 participants. Currently enrolling.
31 December 2026
Quick facts
| Lead sponsor | University of Minnesota |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 40 |
| Start date | 1 October 2022 |
| Primary completion | 31 December 2026 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Interval History
- Physical Examination
- ECAB Assessment
- Gait Assessment
- Specimen Sample Collection
Conditions studied
- DNA Repair Disorder — all drugs for DNA Repair Disorder →
- Cockayne Syndrome — all drugs for Cockayne Syndrome →
- Xeroderma Pigmentosum — all drugs for Xeroderma Pigmentosum →
- Trichothiodystrophy — all drugs for Trichothiodystrophy →
Sponsor
University of Minnesota
Who can join
6 Months and older, any sex, with DNA Repair Disorder or Cockayne Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This will be a single-center, single-arm, non-interventional natural history study to evaluate the longitudinal clinical course, functional outcome measures, and candidate biomarkers for individuals with DNA repair disorders, including Cockayne syndrome (CS), xeroderma pigmentosum (XP), and trichothiodystrophy (TTD).
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05484570
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05484570 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Minnesota
- Last refreshed: 19 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05484570.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing