NCT05484037

Application of Telehealth Technology in Asthma Management

Not yet recruiting NA Last updated 2 August 2022

What this trial tests

NA trial testing CANATEXTS in Asthma Exacerbation in 620 participants. Not yet recruiting.

Timeline

1 March 2023

Primary endpoint
28 February 2026

30 May 2026

Quick facts

Lead sponsor	University of British Columbia
Phase	NA
Status	Not yet recruiting
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	prevention
Enrollment	620
Start date	1 March 2023
Primary completion	28 February 2026
Estimated completion	30 May 2026
Sites	3 locations across Canada

Drugs / interventions tested

• CANATEXTS

Conditions studied

• Asthma Exacerbation — all drugs for Asthma Exacerbation →
• Quality of Life — all drugs for Quality of Life →
• Medication Adherence — all drugs for Medication Adherence →

Sponsor

University of British Columbia

Who can join

Adults 19 to 80, any sex, with Asthma Exacerbation or Quality of Life. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Background: While effective treatments are available, asthma control is sub-optimal for many asthma patients. To help patients self-manage their asthma symptoms, provision of an asthma action plan (AAP) in written format (wAAP), with instructions on managing worsening asthma symptoms is recommended, as a standard of care; however, only about half of patients correctly adhere to their AAP. Canadian Asthma Text Messaging Study (CANATEXTS) is a Telehealth (TH) intervention facilitating access to an electronic AAP (eAAP) via a mobile device. In a feasibility study to assess the safety and efficacy of CANATEXTS, an 18% reduction in the relative risk of exacerbation was observed among the intervention group compared to control group. This study will assess the effectiveness of CANATEXTS on asthma outcomes in a Canada-wide study.

Methods: This is a superiority a 2-arm, multi-site randomized control trial (RCT). This study aims to determine if CANATEXTS reduces asthma exacerbation over a 12-month period, improves asthma control, quality of life (QoL) and medication adherence, and is cost-effective. The intervention includes access to an electronic asthma action plan (eAAP) on patients' mobile devices, disease-related education, and weekly reminders via a Short messaging system (SMS) interface. The study will include 620 adult participants with asthma recruited from 14 respiratory clinics across Canada. Participants will be randomly assigned to either Intervention group (eAAP) or Control groups (wAAP). All outcomes of interest will be assessed during three in-person assessments (baseline, 6-month, and 12-month) and two telephone follow-ups (3-month and 9-month). Data will be analyzed with a linear mixed-effects model across all time points. Discussion: TH has the potential to improve adult individuals with asthma's engagement in self-management practices. Our feasibility study showed TH could yield a reduction in asthma exacerbation. If the proposed TH intervention is found to be effective for asthma management in a nation-wide trial, it will generate evidence to support integration of TH in asthma self-management. This study will also provide important information on the cost-effectiveness of CANATEXTS when compared to standard asthma care.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.