NCT05481450 is a NA clinical trial of Nutritears® in Dry Eye, sponsored by Applied Science & Performance Institute.

Who is sponsoring NCT05481450?

NCT05481450 is sponsored by Applied Science & Performance Institute.

What drugs are being tested in NCT05481450?

Interventions in NCT05481450: Nutritears®, Placebo.

What condition does NCT05481450 study?

NCT05481450 studies Dry Eye, Dry Eye Syndromes.

Is NCT05481450 still recruiting?

NCT05481450 is currently completed. Last updated 26 May 2023.

Last reviewed 2023-05-26 · How we verify

NCT05481450

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Efficacy and Safety Safety of Nutritears® in Adults With Dry Eye Syndrome

Completed NA Last updated 26 May 2023

What this trial tests

NA trial testing Nutritears® in Dry Eye in 131 participants. Completed in 22 May 2023.

Timeline

15 August 2022

Primary endpoint
15 May 2023

22 May 2023

Quick facts

Lead sponsor	Applied Science & Performance Institute
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	131
Start date	15 August 2022
Primary completion	15 May 2023
Estimated completion	22 May 2023
Sites	3 locations across United States

Drugs / interventions tested

Nutritears®
Placebo

Conditions studied

Dry Eye — all drugs for Dry Eye →
Dry Eye Syndromes — all drugs for Dry Eye Syndromes →

Sponsor

Applied Science & Performance Institute — full company profile →

Who can join

Adults 18 to 65, any sex, with Dry Eye or Dry Eye Syndromes. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a prospective, randomized, double-blind, parallel, placebo-controlled, clinical interventional study. The purpose of this study is to evaluate the efficacy and safety of Nutritears®, a dietary supplement of OmniActive Health Technologies, in adult subjects with dry eye syndrome (DES). Subjects shall be instructed to consume one capsule of their assigned investigational study product every morning after the breakfast, at the same time every day, for 56 days (8 weeks).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

A novel multi-ingredient supplement significantly improves ocular symptom severity and tear production in patients with dry eye disease: results from a randomized, placebo-controlled clinical trial.
Gioia N, Gerson J, Ryan R, Barbour K, et al · · 2024 · cited 2× · PMID 38984118 · DOI 10.3389/fopht.2024.1362113

Verify or expand the search:

Other recruiting trials for Dry Eye

Currently open trials in the same condition.

NCT07366944 — PCOS and Problem of Eye Dryness: Is There a Benefit From Lifetyle Changes · NA · recruiting
NCT07329712 — Comparing Tear Proteomics Profile in Dry Eye Disease pre-and Post-treatment With Low Level Light Therapy · recruiting
NCT07266948 — Impact of TRYPTYR on a Patient's Quality of Life and Ability to Perform Work · Phase 4 · recruiting
NCT07298811 — Preliminary Clinical Study of the Effectiveness and Safety of Ocular Surface Microbiota Transplantation in the Treatment · Phase 1, PHASE2 · recruiting
NCT07135193 — Evaluation of the Protective Effects of Cordyceps Cicadae on Visual Function and Anti-Fatigue Performance in Esports Ath · NA · active not recruiting

Other Applied Science & Performance Institute trials

Trials by the same sponsor.

NCT07224867 — The Effects of Liquid IV's Multi-Ingredient Recovery Supplement on Muscle Recovery Following Exercise · NA · not yet recruiting
NCT07495592 — The Acute Effects of Onnit Alpha Brain on Cognition and Mood States · NA · not yet recruiting
NCT07225608 — The Acute Effects of Liquid IV's Pre-Workout Supplement on Muscle Endurance & Strength, Energy, and Cognition · NA · completed
NCT06959472 — Impact of Hyperarch Fascia Training on Ankle Health and Exercise Performance · NA · completed
NCT06883292 — The Effects of Tyrosol and Creatine on Endurance, Strength, and Fatigue Resistance in Healthy Adults · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05481450 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Applied Science & Performance Institute
Last refreshed: 26 May 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05481450.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing