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NCT05480267
A RCT of UBE vs. MIS-TLIF in Lumbar Spondylolisthesis
NA trial testing surgical treatment for lumbar spondylolisthesis in Lumbar Spondylolisthesis in 340 participants. Status unknown.
1 May 2025
Quick facts
| Lead sponsor | Second Affiliated Hospital, School of Medicine, Zhejiang University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 340 |
| Start date | 1 September 2022 |
| Primary completion | 1 May 2025 |
| Estimated completion | 1 September 2025 |
Drugs / interventions tested
- surgical treatment for lumbar spondylolisthesis
Conditions studied
- Lumbar Spondylolisthesis — all drugs for Lumbar Spondylolisthesis →
- Unilateral Biportal Endoscopy — all drugs for Unilateral Biportal Endoscopy →
- Minimally Invasive Technique — all drugs for Minimally Invasive Technique →
- Surgical Treatment — all drugs for Surgical Treatment →
Sponsor
Second Affiliated Hospital, School of Medicine, Zhejiang University
Who can join
Adults 40 to 75, any sex, with Lumbar Spondylolisthesis or Unilateral Biportal Endoscopy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Unilateral biportal endoscopy (UBE) is a new spinal minimally invasive technique improved for the treatment of lumbar spondylolisthesis (LSP). The present study aims to establish a multicenter, large sample, randomized controlled study to explore the technical advantages and surgical indications of this new technique in the treatment of LSP by comparing with the classical minimally invasive posterior spinal interbody fusion; to compare the postoperative clinical and imaging results and analyze the surgical complications and preventive measures.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Endoscopic Spine Surgery: A Scoping Review of the Literature.
Mulhall D, Kow CY, Veilleux C, Oliveira Masson A, et al · · 2026 · PMID 41806368 · DOI 10.1177/21925682261434579
Verify or expand the search:
- PubMed search for NCT05480267
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Lumbar Spondylolisthesis
Currently open trials in the same condition.
- NCT05029726 — Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery · Phase 4 · recruiting
- NCT05945550 — Comparison of Complication Rates Between Initial and Re-operative Anterior Lumbar Interbody Fusion Surgery: Is There a D · active not recruiting
- NCT03570801 — SLIP II Registry: Spinal Laminectomy Versus Instrumented Pedicle Screw Fusion · NA · active not recruiting
Other Second Affiliated Hospital, School of Medicine, Zhejiang University trials
Trials by the same sponsor.
- NCT07445152 — Research on Construction and Verification of Multimodal Medical Imaging Large Model · not yet recruiting
- NCT06775665 — A Real-World Study on Hypertrophic Cardiomyopathy in Chinese Population · not yet recruiting
- NCT07533422 — Rescue Reatment of Helicobacter Pylori Based on Fecal Antimicrobial Resistance Gene Testing · NA · not yet recruiting
- NCT07487285 — A Non-inferiority Study of Laser Combined With Ultrasonic Debridement Therapy (LCUDT) Versus Manual Combined With Ultras · NA · not yet recruiting
- NCT07505186 — Camrelizumab, Chemotherapy and Ivarmacitinib in Patients With Resectable Esophageal Squamous Cell Carcinoma · Phase 2 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05480267 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Second Affiliated Hospital, School of Medicine, Zhejiang University
- Last refreshed: 29 July 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05480267.
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