NCT05479565

Relationship of Reduced Arterial Stiffness and Hs-CRP With GDM.

Completed Last updated 5 December 2023

What this trial tests

trial testing venous blood sample for determining the value of highly sensitive C-reactive C protein from serum in Gestational Diabetes in 100 participants. Completed in 1 September 2023.

Timeline

1 September 2020

Primary endpoint
1 September 2023

1 September 2023

Quick facts

Lead sponsor	University of Mostar
Status	Completed
Study type	OBSERVATIONAL
Enrollment	100
Start date	1 September 2020
Primary completion	1 September 2023
Estimated completion	1 September 2023
Sites	1 location across Bosnia and Herzegovina

Drugs / interventions tested

• venous blood sample for determining the value of highly sensitive C-reactive C protein from serum

Conditions studied

• Gestational Diabetes — all drugs for Gestational Diabetes →

Sponsor

University of Mostar

Who can join

Adults 18 to 35, female only, with Gestational Diabetes. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Research hypotheses

1. The arterial stiffness in pregnant women with gestational diabetes is reduced compared to healthy pregnant women.
2. The values of highly sensitive CRP in pregnant women with gestational diabetes are higher compared to healthy pregnant women.
3. The arterial stiffness in test subjects with previous gestational diabetes was reduced compared to test subjects with a previously normal OGTT during pregnancy.
4. The values of highly sensitive CRP in subjects with previous gestational diabetes are higher compared to subjects with previously normal OGTT during pregnancy.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Arterial stiffness in women with gestational diabetes mellitus in pregnancy and postpartum.
   Dugandžić Šimić A, Mandrapa V, Bošković A, Krešić T, et al · · 2026 · cited 1× · PMID 40839123 · DOI 10.1007/s00508-025-02581-z