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NCT05473455
Value of Follicular Flushing. Randomised Controlled Trial
NA trial testing Experimental: Follicular aspiration with addition of follicular flushing. in Infertility in 105 participants. Completed in 31 December 2022.
30 December 2022
Quick facts
| Lead sponsor | Eugonia |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 105 |
| Start date | 15 July 2022 |
| Primary completion | 30 December 2022 |
| Estimated completion | 31 December 2022 |
| Sites | 1 location across Greece |
Drugs / interventions tested
- Experimental: Follicular aspiration with addition of follicular flushing.
Conditions studied
- Infertility — all drugs for Infertility →
Sponsor
Eugonia — full company profile →
Who can join
Adults 18 to 43, female only, with Infertility. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to evaluate whether the addition of follicular flushing to the initial aspiration during oocyte retrieval increases the number of oocytes retrieved in women undergoing ovarian stimulation.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Follicular flushing increases the number of oocytes retrieved: a randomized controlled trial.
Lainas GT, Lainas TG, Makris AA, Xenariou MV, et al · · 2023 · cited 6× · PMID 37632249 · DOI 10.1093/humrep/dead169 -
A systematic review and meta-analysis of randomized controlled studies comparing follicular flushing versus aspiration during oocyte retrieval in IVF cycles.
El-Goly NA, Maged AM, Essam A, Shoab A. · · 2025 · cited 1× · PMID 40165322 · DOI 10.1186/s40834-025-00351-w
Verify or expand the search:
- PubMed search for NCT05473455
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Infertility
Currently open trials in the same condition.
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- NCT07369362 — To Investigate if the Harvester® Improves Sperm Motility and Blastocyst Utilization (the Percent of Fertilized Eggs That · NA · active not recruiting
- NCT07153367 — Using a Fixed Dosage of Follitropin Delta for Ovarian Stimulation for Intrauterine Insemination: Rekovelle for Intrauter · Phase 2 · recruiting
Other Eugonia trials
Trials by the same sponsor.
- NCT06019494 — Comparison of 2 Different Flow Rates During Oocyte Retrieval · NA · completed
- NCT03610009 — 2D Versus SonoAVC Scanning in High Responders · NA · unknown
- NCT03354858 — Follicular Flushing Versus Direct Aspiration · completed
- NCT03353285 — Effect of Follicle Flushing on Oocyte Fertilization Rate · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05473455 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Eugonia
- Last refreshed: 30 March 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05473455.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing