Last reviewed · How we verify
NCT05470907: HERICC
Registry for Hemoperfusion of Covid-19 ICU Patients
trial testing Hemoperfusion in COVID-19 Acute Respiratory Distress Syndrome in 1,050 participants. Completed in 5 February 2025.
1 February 2025
Quick facts
| Lead sponsor | Croatian Society for Organ Support |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 1,050 |
| Start date | 21 July 2022 |
| Primary completion | 1 February 2025 |
| Estimated completion | 5 February 2025 |
| Sites | 1 location across Croatia |
Drugs / interventions tested
- Hemoperfusion
Conditions studied
- COVID-19 Acute Respiratory Distress Syndrome — all drugs for COVID-19 Acute Respiratory Distress Syndrome →
- Viral Disease — all drugs for Viral Disease →
- Critical Illness — all drugs for Critical Illness →
- Multi Organ Failure — all drugs for Multi Organ Failure →
Sponsor
Croatian Society for Organ Support
Who can join
18 and older, any sex, with COVID-19 Acute Respiratory Distress Syndrome or Viral Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The ongoing COVID-19 pandemic caused high hospitalization and mortality rates especially in critically ill patients. Unfortunately, there is no present study with a large number of patients that would offer us clear answers on the treatment of ICU COVID-19 patients with adsorption filters, extracorporeal methods and the hemoperfusion method. The purpose of this registry study is to investigate the effectiveness and safety of the extracorporeal blood purification and hemoperfusion/hemadsorption filters in treating of critically ill COVID-19 patients.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Seraph® filter effectiveness in the treatment of circuit-related infections in ECMO patients-a single-center report.
Lovric D, Situm I, Nedeljkovic V, Mogus M, et al · · 2025 · PMID 41179859 · DOI 10.3389/fmed.2025.1664552
Verify or expand the search:
- PubMed search for NCT05470907
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Hemoperfusion
Trials testing the same drug.
- NCT05608096 — European Registry for Hemadsorption in Sepsis With the Seraph Filter · unknown
- NCT04007484 — Hemoperfusion in Acute Type A Aortic Dissection Patients Undergoing Aortic Arch Operation (HPAO) · NA · unknown
- NCT03314909 — Initial Hemopurification Strategy for Acute Paraquat Poisoning in Adults · NA · unknown
Other recruiting trials for COVID-19 Acute Respiratory Distress Syndrome
Currently open trials in the same condition.
- NCT06402318 — Passive Detection- SARS-CoV-2 (COVID-19) A&M Breathalyzer (PROTECT Kiosk) for Operational Medicine · recruiting
- NCT05765396 — SARS-CoV-2/COVID-19 Study of Next Generation Non-Invasive Passive Detection Technologies · active not recruiting
- NCT04964115 — Post Acute Sequelae of COVID-19 · active not recruiting
- NCT05164744 — Cardiac Magnetic Resonance Tissue Characterization in COVID-19 Survivors · recruiting
- NCT04896853 — Treatment of Respiratory Complications Associated With COVID19,Influenza ,Metapneumovirus,RSV Infection Using ProTrans® · Phase 1 · active not recruiting
Other Croatian Society for Organ Support trials
Trials by the same sponsor.
- NCT07052617 — Impact of Different CRRT Modalities, Dosing Strategies, and Timing on Kidney Recovery and Prolonged Kidney Dysfunction · not yet recruiting
- NCT05608096 — European Registry for Hemadsorption in Sepsis With the Seraph Filter · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05470907 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Croatian Society for Organ Support
- Last refreshed: 13 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05470907.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing