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NCT05469984
Comparing Two Prophylactic Antibiotic Protocols in Women With Term Prolonged Pre-labor Rupture of Membrane and Preterm Labor
NA trial testing Ampicillin Only Product in Preterm Labor With Preterm Delivery in 600 participants. Currently enrolling.
25 September 2025
Quick facts
| Lead sponsor | Western Galilee Hospital-Nahariya |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 600 |
| Start date | 25 November 2022 |
| Primary completion | 25 September 2025 |
| Estimated completion | 26 September 2025 |
| Sites | 1 location across Israel |
Drugs / interventions tested
- Ampicillin Only Product — full drug profile →
- ampicillin plus gentamicin — full drug profile →
Conditions studied
- Preterm Labor With Preterm Delivery — all drugs for Preterm Labor With Preterm Delivery →
- Premature Rupture of Membranes Prolonged — all drugs for Premature Rupture of Membranes Prolonged →
Sponsor
Western Galilee Hospital-Nahariya
Who can join
Adults 18 to 48, female only, with Preterm Labor With Preterm Delivery or Premature Rupture of Membranes Prolonged. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This randomized prospective trial aimed to compare 2 prophylactic antibiotic regiment (ampicillin alone versus ampicillin plus gentamycin) in term prolonged pre-labor rupture of membrane and in preterm deliveries and examine related obstetrical outcome and infectious morbidity
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05469984
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Related trials
Other Western Galilee Hospital-Nahariya trials
Trials by the same sponsor.
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- NCT06578754 — Validation Testing for Plasma Oxalate Levels in the Biochemical Laboratory at the Galilee Medical Center, in Collaborati · not yet recruiting
- NCT07311395 — Local Subcutaneous Gentamicin for Prevention of Surgical Site Infection After Elective Cesarean Section · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05469984 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Western Galilee Hospital-Nahariya
- Last refreshed: 6 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05469984.
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