Association Between Peripheral Muscle Function and Quality of Life in Obese Subjects (OVALIA)

NCT05467020 COMPLETED

The assessment of health status and physical function is fundamental in patients with obesity, as they play an important role among the various factors influencing the quality of life in this population. Several studies have shown an association between high BMI values and a significant deterioration in quality of life, especially in women. Excess body fat in obese patients seems to be responsible for muscle atrophy. This causal link is probably related to dysfunctions in adipose tissue, leading to a decrease in the expression of proteins responsible for muscle contraction. The recent literature highlights an alteration in quality of life, particularly in obese and elderly subjects, for which changes in muscle function are partly responsible. Changes in muscle function can be assessed by simple, rapid and non-invasive tools. They could be used to identify obese subjects at risk of they could be used to identify obese subjects at risk of muscle atrophy, to stratify the risk, and to propose prophylactic intervention or early management. The main objective of this study is to evaluate the association between structural alteration of the quadriceps and quality of life in obese patients. The secondary objectives are to evaluate : * The association between quadriceps thickness and quality of life ; * The association between grip strength and quality of life ; * The association between quadriceps strength and quality of life ; * The association between quadriceps strength and ultrasound measurements of the quadriceps. This is a prospective, monocenter, observationnal and cohort study. All outpatients for nutrition assessment will be included.

Details

Lead sponsor	Hopital Forcilles
Status	COMPLETED
Enrolment	84
Start date	Fri Apr 22 2022 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Mon Oct 02 2023 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Obesity

Countries

France