NCT05465291

Neuromuscular Electrical Stimulation in Mechanically Ventilated Patients

Completed NA Last updated 11 April 2023

What this trial tests

NA trial testing Exercise group in Neuromuscular Electrical Stimulation in 120 participants. Completed in 18 February 2023.

Timeline

18 October 2022

Primary endpoint
18 February 2023

18 February 2023

Quick facts

Lead sponsor	Damanhour University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	supportive care
Enrollment	120
Start date	18 October 2022
Primary completion	18 February 2023
Estimated completion	18 February 2023
Sites	1 location across Egypt

Drugs / interventions tested

• Exercise group
• Neuromuscular Electrical Muscle Stimulation group
• Neuromuscular Electrical Muscle Stimulation and Exercise group

Conditions studied

• Neuromuscular Electrical Stimulation — all drugs for Neuromuscular Electrical Stimulation →
• ICU Acquired Muscle Weakness — all drugs for ICU Acquired Muscle Weakness →

Sponsor

Damanhour University

Who can join

18 and older, any sex, with Neuromuscular Electrical Stimulation or ICU Acquired Muscle Weakness. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Intensive care unit-acquired muscle weakness (ICUAMW) is a common problem following an ICU admission and is associated with prolonged hospitalization, delayed weaning and increased mortality. Up to 25% of patients requiring mechanical ventilation (MV) for greater than 7 days develop ICUAW, and this figure may rise to 50-100% in the septic population. Long-term follow-up studies of survivors of critical illness have demonstrated significantly impaired health-related quality of life and physical functioning up to 5 years after ICU discharge, with weakness being the most commonly reported physical limitation. Early rehabilitation has been shown to be safe and feasible; however, commencement is often delayed due to a patient's inability to cooperate. An intervention that begins early in ICU admission without the need for patient volition may be beneficial in attenuating muscle wasting. Therefore, this study aims to evaluate the effect of neuromuscular electrical stimulation and early physical activity on ICU acquired muscle weakness in mechanically ventilated patient

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.