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NCT05455021: REACTIVATE I
Feasibility Study of the Vessel Restoration System (VRS) for the Treatment of Atherosclerotic Lesions in the Superficial Femoral Artery (SFA) and/or Popliteal Artery (PA) After Sub-optimal Percutaneous Transluminal Angioplasty (PTA) or Atherectomy: REACTIVATE I
NA trial testing Vessel Restoration System (VRS) in PAD - Peripheral Arterial Disease in 50 participants. Participants enrolled and being followed up; not accepting new ones.
15 November 2026
Quick facts
| Lead sponsor | Alucent Biomedical |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | sequential |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 50 |
| Start date | 15 November 2021 |
| Primary completion | 15 November 2026 |
| Estimated completion | 15 November 2026 |
| Sites | 2 locations across Australia |
Drugs / interventions tested
- Vessel Restoration System (VRS)
Conditions studied
- PAD - Peripheral Arterial Disease — all drugs for PAD - Peripheral Arterial Disease →
Sponsor
Alucent Biomedical
Who can join
18 and older, any sex, with PAD - Peripheral Arterial Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Feasibility Study of the Vessel Restoration System (VRS) for the Treatment of Atherosclerotic Lesions in the Superficial Femoral Artery (SFA) and/or Popliteal Artery (PA) after Sub-optimal percutaneous transluminal angioplasty (PTA) or Atherectomy: REACTIVATE I
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05455021
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Vessel Restoration System (VRS)
Trials testing the same drug.
- NCT05454995 — Feasibility Study of the Vessel Restoration System (VRS): ACTIVATE II · NA · active not recruiting
Other recruiting trials for PAD - Peripheral Arterial Disease
Currently open trials in the same condition.
- NCT07130526 — Distrupt Stiffness Trial · NA · recruiting
- NCT06182397 — Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease · NA · recruiting
- NCT05454995 — Feasibility Study of the Vessel Restoration System (VRS): ACTIVATE II · NA · active not recruiting
- NCT04792320 — Oral Absorbent and Probiotics in CKD Patients With PAD on Gut Microbiota, IncRNA, Metabolome, and Vascular Function · NA · recruiting
Other Alucent Biomedical trials
Trials by the same sponsor.
- NCT05462223 — Alucent Vessel Restoration System for AVF · NA · unknown
- NCT05454995 — Feasibility Study of the Vessel Restoration System (VRS): ACTIVATE II · NA · active not recruiting
- NCT04188262 — Natural Vascular Scaffold (NVS) Therapy for Treatment of Atherosclerotic Lesions (Activate I) · Phase 1 · completed
- NCT03148808 — Natural Vascular Scaffold (NVS) Therapy · Phase 1 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05455021 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Alucent Biomedical
- Last refreshed: 16 January 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05455021.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing