Can Biotin Supplementation be Used to Mask hCG Abuse?

NCT05450900 EARLY_PHASE1 COMPLETED

This sponsor is an anti-doping laboratory tasked with testing athlete samples for prohibited substances by the World Anti-Doping Agency and other agencies. This study is intended to measure: 1. Urinary/serum hCG (human chorionic gonadotropin) and urinary biotin concentrations in both treatment groups before, during, and after hCG intervention using standard immunoassay methods 2. To monitor hCG in both treatment groups before and after diafiltration of urine samples prior to analysis 3. To compare urinary and serum detectability (detection window, sensitivity) of hCG abuse in the hCG-only group compared to the hCG + biotin group

Details

Lead sponsor	Sports Medicine Research and Testing Laboratory
Phase	EARLY_PHASE1
Status	COMPLETED
Enrolment	10
Start date	Thu Oct 27 2022 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Thu Feb 02 2023 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Healthy

Interventions

• Choriogonadotropin Alpha
• biotin
• Microcellulose filler

Countries

United States