NCT05450120

Rehabilitation of Critically Ill Patients With SARS-CoV-2 Variants in ICU With Limited Resources

Status unknown NA Last updated 8 August 2022

What this trial tests

NA trial testing Functional Rehabilitation in COVID-19 Acute Respiratory Distress Syndrome in 88 participants. Status unknown.

Timeline

1 May 2020

Primary endpoint
1 October 2020

1 December 2022

Quick facts

Lead sponsor	Universidade Federal de Sao Carlos
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	88
Start date	1 May 2020
Primary completion	1 October 2020
Estimated completion	1 December 2022
Sites	1 location across Brazil

Drugs / interventions tested

• Functional Rehabilitation
• Neuromuscular Electrical Stimulation

Conditions studied

• COVID-19 Acute Respiratory Distress Syndrome — all drugs for COVID-19 Acute Respiratory Distress Syndrome →

Sponsor

Universidade Federal de Sao Carlos

Who can join

18 and older, any sex, with COVID-19 Acute Respiratory Distress Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Acute rehabilitation in critically ill patients can improve post-intensive care unit (post-ICU) physical function. Scientific evidence has considered neuromuscular electrical stimulation (NMES) as a promising approach for the early rehabilitation of patients during and/or after ICU.

Neuromuscular electrostimulation can be an alternative form of muscle exercise that helps to gain strength in critically ill patients with COVID -19, due to the severe weakness that patients experience due to longer MV, analgesia and NMB duration. Thus, the general objective of evaluating the effects of an early rehabilitation protocol on the strength and functionality of patients affected by SARS-CoV-2 variants and specifically compare the effectiveness of NMES associated with the functional rehabilitation protocol(FR). Also, describe demographics, clinical status, ICU therapies, mortality estimates and Hospital outcomes, of every patients admitted in ICU during the observation periods.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.