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NCT05448586
Opioid Free Anaesthesia in Oncologic Gynaecological Surgery: Is There Any Benefit?
trial testing Opioid in Cervix Cancer in 132 participants. Completed in 30 January 2021.
30 January 2021
Quick facts
| Lead sponsor | Instituto de Investigación Hospital Universitario La Paz |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 132 |
| Start date | 2 February 2019 |
| Primary completion | 30 January 2021 |
| Estimated completion | 30 January 2021 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Opioid
Conditions studied
- Cervix Cancer — all drugs for Cervix Cancer →
- Endometrial Cancer — all drugs for Endometrial Cancer →
- Ovarian Cancer — all drugs for Ovarian Cancer →
- Breast Cancer — all drugs for Breast Cancer →
Sponsor
Instituto de Investigación Hospital Universitario La Paz
Who can join
Adults 20 to 91, female only, with Cervix Cancer or Endometrial Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Opioid Free Anesthesia (OFA) is a multimodal anesthesia and emerging technique that spares the use of opioids and involve other adjuvant anesthetics, which have demonstrated in vitro influence on immunologic and inflammatory response, as well as in metastatic progression. For these reasons we believe that OFA may positively influence in oncologic patients postoperative recovery and in its disease progression.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Trial watch: dexmedetomidine in cancer therapy.
Carnet Le Provost K, Kepp O, Kroemer G, Bezu L. · · 2024 · cited 24× · PMID 38481729 · DOI 10.1080/2162402x.2024.2327143
Verify or expand the search:
- PubMed search for NCT05448586
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Opioid
Trials testing the same drug.
- NCT07364864 — Opioid-free Anesthesia as an Alternative to General Anesthesia in Patients Undergoing Duodenopancreatic Surgery by Lapar · NA · not yet recruiting
- NCT06837857 — Prescription Opioids, Brain Structure, and Cognition in Older Adults With Chronic Pain · Phase 2 · recruiting
- NCT06671002 — Comparing Analgesic Regimen Effectiveness and Safety for Surgery for Kids Trial · Phase 4 · recruiting
- NCT06683911 — Opioids Continue to Play a Primary Role in the Management of Perioperative Pain Due to Opioid-Free Anesthesia in Open He · completed
- NCT06199011 — Effect of Esketamine on Depressive Symptoms of Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy · NA · unknown
Other recruiting trials for Cervix Cancer
Currently open trials in the same condition.
- NCT07276360 — Hypofractionated Radiotherapy for the Treatment of Locally Advanced Cervical Cancer in Uganda · Phase 2 · recruiting
- NCT07292818 — Hyaluronic Acid-based Gel Spacers in Gynecologic Malignancies · Phase 1 · recruiting
- NCT07435623 — Late Radiation Toxicities in Cervical and Endometrial Cancer: A Postoperative IMRT/Brachytherapy Study · recruiting
- NCT06904365 — Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women · recruiting
- NCT06416748 — Minimally Invasive Simple Hysterectomy in Low Risk Cervical Cancer · NA · recruiting
Other Instituto de Investigación Hospital Universitario La Paz trials
Trials by the same sponsor.
- NCT06709469 — Phase I Clinical Trial of CART Cell Therapy for Refractory/Relapsed Acute Lymphoblastic Leukemia in Children, Adolescent · Phase 1 · recruiting
- NCT06701825 — Effectiveness and Cost-effectiveness of a Pre-emptive Genotyping Strategy in Patients Receiving Tacrolimus · Phase 4 · recruiting
- NCT06488898 — Abdominal Aortic Aneurysm Stabilization With Truncal Cells: Controlled Clinical Trial With Historical Cohorts · Phase 2 · recruiting
- NCT06273306 — Towards Telemonitoring in Immune-Mediated Inflammatory Diseases: Implementation of a Mixed Attention Model (IMIDOC) · NA · not yet recruiting
- NCT06302647 — Assessing Interest in Web/App Platforms for Early Phase Clinical Trial Recruitment · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05448586 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Instituto de Investigación Hospital Universitario La Paz
- Last refreshed: 7 July 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05448586.
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